mTORC2 Signaling Regulates Nox4-Induced Podocyte Depletion in Diabetes.

Eid, Stéphanie; Boutary, Suzan; Braych, Kawthar; Sabra, Ramzi; Massaad, Charbel; Hamdy, Ahmed; Rashid, Awad; Moodad, Sarah; Block, Karen; Gorin, Yves; Abboud, Hanna E; Eid, Assaad A

Eid, Stéphanie; Boutary, Suzan; Braych, Kawthar; Sabra, Ramzi; Massaad, Charbel; Hamdy, Ahmed; Rashid, Awad; Moodad, Sarah; Block, Karen; Gorin, Yves; Abboud, Hanna E; Eid, Assaad A.

Afiliación

Eid S; 1 Department of Anatomy, Cell Biology and Physiological Sciences, Faculty of Medicine and Medical Center, American University of Beirut , Beirut, Lebanon .
Boutary S; 2 UMR-S 1124 INSERM, Paris Descartes University, Sorbonne Paris Cite University , Centre Interdisciplinaire Chimie Biology, Paris, France .
Braych K; 1 Department of Anatomy, Cell Biology and Physiological Sciences, Faculty of Medicine and Medical Center, American University of Beirut , Beirut, Lebanon .
Sabra R; 1 Department of Anatomy, Cell Biology and Physiological Sciences, Faculty of Medicine and Medical Center, American University of Beirut , Beirut, Lebanon .
Massaad C; 3 Department of Pharmacology and Toxicology, Faculty of Medicine and Medical Center, American University of Beirut , Beirut, Lebanon .
Hamdy A; 2 UMR-S 1124 INSERM, Paris Descartes University, Sorbonne Paris Cite University , Centre Interdisciplinaire Chimie Biology, Paris, France .
Rashid A; 4 Department of Nephrology, Hamad Medical Corporation , Doha, Qatar .
Moodad S; 4 Department of Nephrology, Hamad Medical Corporation , Doha, Qatar .
Block K; 1 Department of Anatomy, Cell Biology and Physiological Sciences, Faculty of Medicine and Medical Center, American University of Beirut , Beirut, Lebanon .
Gorin Y; 5 Department of Medicine, South Texas Veterans Healthcare System and the University of Texas Health Science Center , San Antonio, Texas.
Abboud HE; 5 Department of Medicine, South Texas Veterans Healthcare System and the University of Texas Health Science Center , San Antonio, Texas.
Eid AA; 5 Department of Medicine, South Texas Veterans Healthcare System and the University of Texas Health Science Center , San Antonio, Texas.

Antioxid Redox Signal ; 25(13): 703-719, 2016 11 01.

Article en En | MEDLINE | ID: mdl-27393154

Asunto(s)

Diabetes Mellitus Experimental/complicaciones; Diabetes Mellitus Tipo 1/complicaciones; Glucosa/farmacología; Complejos Multiproteicos/metabolismo; NADPH Oxidasas/genética; Podocitos/citología; Serina-Treonina Quinasas TOR/metabolismo; Animales; Apoptosis; Proteínas Portadoras/metabolismo; Supervivencia Celular/efectos de los fármacos; Células Cultivadas; Diabetes Mellitus Experimental/genética; Diabetes Mellitus Experimental/metabolismo; Diabetes Mellitus Tipo 1/genética; Diabetes Mellitus Tipo 1/metabolismo; Péptidos y Proteínas de Señalización Intracelular/metabolismo; Masculino; Diana Mecanicista del Complejo 2 de la Rapamicina; Proteínas de la Membrana/metabolismo; Ratones; NADPH Oxidasa 4; NADPH Oxidasas/metabolismo; Podocitos/efectos de los fármacos; Podocitos/metabolismo; Proteínas Proto-Oncogénicas c-akt/metabolismo; Proteína Asociada al mTOR Insensible a la Rapamicina; Especies Reactivas de Oxígeno/metabolismo; Transducción de Señal/efectos de los fármacos

Palabras clave

NADPH oxidases; diabetic nephropathy; mTORC2; reactive oxygen species

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: NADPH Oxidasas / Complejos Multiproteicos / Diabetes Mellitus Experimental / Diabetes Mellitus Tipo 1 / Podocitos / Serina-Treonina Quinasas TOR / Glucosa Límite: Animals Idioma: En Revista: Antioxid Redox Signal Asunto de la revista: METABOLISMO Año: 2016 Tipo del documento: Article País de afiliación: Líbano Pais de publicación: Estados Unidos

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google