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[Etiology and long-term course of subclavian vein thrombosis with reference to acute therapy]. / Atiologie und Langzeitverlauf bei Subclavia-Venenthrombose unter Berücksichtigung der Akuttherapie.
Häuptli, W; Schmitt, H E; Huber, P; Zemp, E; Widmer, L K.
Afiliación
  • Häuptli W; Abteilung für Angiologie, Universitätsspital Basel.
Schweiz Med Wochenschr ; 119(20): 647-52, 1989 May 20.
Article en De | MEDLINE | ID: mdl-2740879
Contrary to deep venous thrombosis of the lower extremity, subclavian vein thrombosis (SVT) is rather rare. Although the problem has been known for more than 100 years, the rarity of its incidence accounts for the persistent uncertainty concerning the indication and modalities of acute therapy as well as the long-term course. In the majority of 96 patients observed between 1976 and 1983 SVT was due to central venous catheter, neoplasm and thoracic outlet syndrome. 2 of 96 patients developed pulmonary embolism. 45 patients without malignancy were available for follow-up studies. Acute therapy included anticoagulation in 27, fibrinolysis in 10 and rib resection in 8 cases. The mean follow-up averaged 6.3 years and confirmed a favorable course independent of the acute therapy modality. There were none of the trophic alterations so often found in the lower extremity and no patient was unable to work as a consequence of SVT. However, minor late sequelae occurred quite frequently: slight symptoms in one third, and minor incapacity for sport in 25% of the cases. 75% of the patients showed clinical signs of stasis, such as venous bypass circulation, edema and/or cyanosis. The average post-thrombotic score (1.3 out of a possible 4) confirms the minor significance of the findings. A rather important reduction in venous backflow was found by plethysmography in 4% of the patients. We favor immediate anticoagulation, mainly to cover the risk of pulmonary embolism. This should be continued for at least 3 months in order to prevent early recurrence of thrombosis.(ABSTRACT TRUNCATED AT 250 WORDS)
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Vena Subclavia / Trombosis Tipo de estudio: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adolescent / Adult / Aged / Aged80 / Child / Female / Humans / Male / Middle aged Idioma: De Revista: Schweiz Med Wochenschr Año: 1989 Tipo del documento: Article Pais de publicación: Suiza
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Vena Subclavia / Trombosis Tipo de estudio: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adolescent / Adult / Aged / Aged80 / Child / Female / Humans / Male / Middle aged Idioma: De Revista: Schweiz Med Wochenschr Año: 1989 Tipo del documento: Article Pais de publicación: Suiza