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Engineering and optimising deaminase fusions for genome editing.
Yang, Luhan; Briggs, Adrian W; Chew, Wei Leong; Mali, Prashant; Guell, Marc; Aach, John; Goodman, Daniel Bryan; Cox, David; Kan, Yinan; Lesha, Emal; Soundararajan, Venkataramanan; Zhang, Feng; Church, George.
Afiliación
  • Yang L; Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA.
  • Briggs AW; Program in Biological and Biomedical Sciences, Harvard Medical School, Boston, Massachusetts 02115, USA.
  • Chew WL; eGenesis Inc., 1 Kendal Square, Building 200, Cambridge Biolabs, Cambridge, Massachusetts 02139, USA.
  • Mali P; Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA.
  • Guell M; Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA.
  • Aach J; Program in Biological and Biomedical Sciences, Harvard Medical School, Boston, Massachusetts 02115, USA.
  • Goodman DB; Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA.
  • Cox D; Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA.
  • Kan Y; eGenesis Inc., 1 Kendal Square, Building 200, Cambridge Biolabs, Cambridge, Massachusetts 02139, USA.
  • Lesha E; Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA.
  • Soundararajan V; Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA.
  • Zhang F; Harvard-MIT Division of Health Science and Technology, Cambridge, Massachusetts 02139, USA.
  • Church G; Harvard-MIT Division of Health Science and Technology, Cambridge, Massachusetts 02139, USA.
Nat Commun ; 7: 13330, 2016 11 02.
Article en En | MEDLINE | ID: mdl-27804970
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas Recombinantes de Fusión / Ingeniería Genética / Citidina Desaminasa / Edición Génica Límite: Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas Recombinantes de Fusión / Ingeniería Genética / Citidina Desaminasa / Edición Génica Límite: Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido