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Integrated Activity and Genetic Profiling of Secreted Peptidases in Cryptococcus neoformans Reveals an Aspartyl Peptidase Required for Low pH Survival and Virulence.
Clarke, Starlynn C; Dumesic, Phillip A; Homer, Christina M; O'Donoghue, Anthony J; La Greca, Florencia; Pallova, Lenka; Majer, Pavel; Madhani, Hiten D; Craik, Charles S.
Afiliación
  • Clarke SC; Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, California, United States of America.
  • Dumesic PA; Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, California, United States of America.
  • Homer CM; Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, California, United States of America.
  • O'Donoghue AJ; Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, California, United States of America.
  • La Greca F; Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, California, United States of America.
  • Pallova L; Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Prague, Czech Republic.
  • Majer P; Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Prague, Czech Republic.
  • Madhani HD; Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, California, United States of America.
  • Craik CS; Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, California, United States of America.
PLoS Pathog ; 12(12): e1006051, 2016 Dec.
Article en En | MEDLINE | ID: mdl-27977806
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas Fúngicas / Criptococosis / Cryptococcus neoformans / Proteasas de Ácido Aspártico Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: PLoS Pathog Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas Fúngicas / Criptococosis / Cryptococcus neoformans / Proteasas de Ácido Aspártico Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: PLoS Pathog Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos