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Multi-level suppression of receptor-PI3K-mTORC1 by fatty acid synthase inhibitors is crucial for their efficacy against ovarian cancer cells.
Wagner, Renate; Stübiger, Gerald; Veigel, Daniel; Wuczkowski, Michael; Lanzerstorfer, Peter; Weghuber, Julian; Karteris, Emmanouil; Nowikovsky, Karin; Wilfinger-Lutz, Nastasia; Singer, Christian F; Colomer, Ramón; Benhamú, Bellinda; López-Rodríguez, María Luz; Valent, Peter; Grunt, Thomas W.
Afiliación
  • Wagner R; Division of Oncology, Department of Medicine I, Medical University Vienna, Vienna, Austria.
  • Stübiger G; Comprehensive Cancer Center, Medical University Vienna, Vienna, Austria.
  • Veigel D; Comprehensive Cancer Center, Medical University Vienna, Vienna, Austria.
  • Wuczkowski M; Department of Biomedical Imaging and Image-guided Therapy, Medical University Vienna, Vienna, Austria.
  • Lanzerstorfer P; Center for Biomarker Research in Medicine, Graz, Austria.
  • Weghuber J; Division of Oncology, Department of Medicine I, Medical University Vienna, Vienna, Austria.
  • Karteris E; Comprehensive Cancer Center, Medical University Vienna, Vienna, Austria.
  • Nowikovsky K; Department of Biomedical Imaging and Image-guided Therapy, Medical University Vienna, Vienna, Austria.
  • Wilfinger-Lutz N; Center for Biomarker Research in Medicine, Graz, Austria.
  • Singer CF; University of Applied Sciences Upper Austria, School of Engineering and Environmental Sciences, Wels, Austria.
  • Colomer R; University of Applied Sciences Upper Austria, School of Engineering and Environmental Sciences, Wels, Austria.
  • Benhamú B; Department of Biosciences, School of Health Sciences and Social Care, Brunel University London, Uxbridge, UK.
  • López-Rodríguez ML; Division of Oncology, Department of Medicine I, Medical University Vienna, Vienna, Austria.
  • Valent P; Comprehensive Cancer Center, Medical University Vienna, Vienna, Austria.
  • Grunt TW; Division of Oncology, Department of Medicine I, Medical University Vienna, Vienna, Austria.
Oncotarget ; 8(7): 11600-11613, 2017 Feb 14.
Article en En | MEDLINE | ID: mdl-28086243
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Ováricas / Complejos Multiproteicos / Inhibidores Enzimáticos / Ácido Graso Sintasas / Serina-Treonina Quinasas TOR / Inhibidores de las Quinasa Fosfoinosítidos-3 Límite: Female / Humans Idioma: En Revista: Oncotarget Año: 2017 Tipo del documento: Article País de afiliación: Austria Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Ováricas / Complejos Multiproteicos / Inhibidores Enzimáticos / Ácido Graso Sintasas / Serina-Treonina Quinasas TOR / Inhibidores de las Quinasa Fosfoinosítidos-3 Límite: Female / Humans Idioma: En Revista: Oncotarget Año: 2017 Tipo del documento: Article País de afiliación: Austria Pais de publicación: Estados Unidos