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Radiation Resistance in KRAS-Mutated Lung Cancer Is Enabled by Stem-like Properties Mediated by an Osteopontin-EGFR Pathway.
Wang, Meng; Han, Jing; Marcar, Lynnette; Black, Josh; Liu, Qi; Li, Xiangyong; Nagulapalli, Kshithija; Sequist, Lecia V; Mak, Raymond H; Benes, Cyril H; Hong, Theodore S; Gurtner, Kristin; Krause, Mechthild; Baumann, Michael; Kang, Jing X; Whetstine, Johnathan R; Willers, Henning.
Afiliación
  • Wang M; Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.
  • Han J; Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.
  • Marcar L; Jinan Municipal Center for Disease Control and Prevention, Shandong, China.
  • Black J; Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.
  • Liu Q; University of Colorado School of Medicine, Aurora, Colorado.
  • Li X; Center for Cancer Research, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts.
  • Nagulapalli K; Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.
  • Sequist LV; Laboratory for Lipid Medicine and Technology, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts.
  • Mak RH; Center for Computational Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts.
  • Benes CH; Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.
  • Hong TS; Department of Radiation Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts.
  • Gurtner K; Center for Cancer Research, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts.
  • Krause M; Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.
  • Baumann M; Department of Radiation Oncology, Medical Faculty and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
  • Kang JX; OncoRay National Center for Radiation Research in Oncology, Dresden, Germany.
  • Whetstine JR; Medical Faculty and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
  • Willers H; Helmholtz-Zentrum Dresden-Rossendorf, Dresden, Germany.
Cancer Res ; 77(8): 2018-2028, 2017 04 15.
Article en En | MEDLINE | ID: mdl-28202526
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas Proto-Oncogénicas p21(ras) / Carcinoma de Pulmón de Células no Pequeñas / Osteopontina / Receptores ErbB / Neoplasias Pulmonares Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans / Male Idioma: En Revista: Cancer Res Año: 2017 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas Proto-Oncogénicas p21(ras) / Carcinoma de Pulmón de Células no Pequeñas / Osteopontina / Receptores ErbB / Neoplasias Pulmonares Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans / Male Idioma: En Revista: Cancer Res Año: 2017 Tipo del documento: Article Pais de publicación: Estados Unidos