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A clinical drug library screen identifies clobetasol propionate as an NRF2 inhibitor with potential therapeutic efficacy in KEAP1 mutant lung cancer.
Choi, E-J; Jung, B-J; Lee, S-H; Yoo, H-S; Shin, E-A; Ko, H-J; Chang, S; Kim, S-Y; Jeon, S-M.
Afiliación
  • Choi EJ; College of Pharmacy, Ajou University, Suwon, Republic of Korea.
  • Jung BJ; College of Pharmacy, Ajou University, Suwon, Republic of Korea.
  • Lee SH; Cancer Cell and Molecular Biology Branch, Research Institute, National Cancer Center, Goyang, Republic of Korea.
  • Yoo HS; College of Pharmacy, Ajou University, Suwon, Republic of Korea.
  • Shin EA; College of Pharmacy, Ajou University, Suwon, Republic of Korea.
  • Ko HJ; College of Pharmacy, Kangwon National University, Chuncheon, Republic of Korea.
  • Chang S; Convergence Research Center for Functional Plant Products, Advanced Institutes of Convergence Technology, Yeongtong-gu, Suwon, Republic of Korea.
  • Kim SY; Department of Biomedical Sciences, University of Ulsan School of Medicine, Asan Medical Center, Seoul, Republic of Korea.
  • Jeon SM; Cancer Cell and Molecular Biology Branch, Research Institute, National Cancer Center, Goyang, Republic of Korea.
Oncogene ; 36(37): 5285-5295, 2017 09 14.
Article en En | MEDLINE | ID: mdl-28504720

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Clobetasol / Factor 2 Relacionado con NF-E2 / Proteína 1 Asociada A ECH Tipo Kelch / Neoplasias Pulmonares / Antiinflamatorios Tipo de estudio: Clinical_trials / Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Oncogene Asunto de la revista: BIOLOGIA MOLECULAR / NEOPLASIAS Año: 2017 Tipo del documento: Article

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Clobetasol / Factor 2 Relacionado con NF-E2 / Proteína 1 Asociada A ECH Tipo Kelch / Neoplasias Pulmonares / Antiinflamatorios Tipo de estudio: Clinical_trials / Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Oncogene Asunto de la revista: BIOLOGIA MOLECULAR / NEOPLASIAS Año: 2017 Tipo del documento: Article