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The pathological Trento variant of alpha-1-antitrypsin (E75V) shows nonclassical behaviour during polymerization.
Miranda, Elena; Ferrarotti, Ilaria; Berardelli, Romina; Laffranchi, Mattia; Cerea, Marta; Gangemi, Fabrizio; Haq, Imran; Ottaviani, Stefania; Lomas, David A; Irving, James A; Fra, Annamaria.
Afiliación
  • Miranda E; Department of Biology and Biotechnologies 'Charles Darwin', Sapienza University of Rome, Italy.
  • Ferrarotti I; Department of Internal Medicine and Therapeutics, Pneumology Unit, University of Pavia, Italy.
  • Berardelli R; Department of Molecular and Translational Medicine, University of Brescia, Italy.
  • Laffranchi M; Department of Molecular and Translational Medicine, University of Brescia, Italy.
  • Cerea M; Department of Biology and Biotechnologies 'Charles Darwin', Sapienza University of Rome, Italy.
  • Gangemi F; Department of Molecular and Translational Medicine, University of Brescia, Italy.
  • Haq I; Department of Molecular and Translational Medicine, University of Brescia, Italy.
  • Ottaviani S; UCL Respiratory and the Institute of Structural and Molecular Biology, University College London, UK.
  • Lomas DA; Center for Diagnosis of Inherited Alpha 1-Antitrypsin Deficiency, Pneumology Unit, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
  • Irving JA; UCL Respiratory and the Institute of Structural and Molecular Biology, University College London, UK.
  • Fra A; UCL Respiratory and the Institute of Structural and Molecular Biology, University College London, UK.
FEBS J ; 284(13): 2110-2126, 2017 07.
Article en En | MEDLINE | ID: mdl-28504839
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Alfa 1-Antitripsina / Deficiencia de alfa 1-Antitripsina / Predisposición Genética a la Enfermedad / Mutación Tipo de estudio: Prognostic_studies Límite: Humans / Male / Middle aged Idioma: En Revista: FEBS J Asunto de la revista: BIOQUIMICA Año: 2017 Tipo del documento: Article País de afiliación: Italia
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Alfa 1-Antitripsina / Deficiencia de alfa 1-Antitripsina / Predisposición Genética a la Enfermedad / Mutación Tipo de estudio: Prognostic_studies Límite: Humans / Male / Middle aged Idioma: En Revista: FEBS J Asunto de la revista: BIOQUIMICA Año: 2017 Tipo del documento: Article País de afiliación: Italia