Ability of a Genomic Classifier to Predict Metastasis and Prostate Cancer-specific Mortality after Radiation or Surgery based on Needle Biopsy Specimens.

Nguyen, Paul L; Haddad, Zaid; Ross, Ashley E; Martin, Neil E; Deheshi, Samineh; Lam, Lucia L C; Chelliserry, Jijumon; Tosoian, Jeffrey J; Lotan, Tamara L; Spratt, Daniel E; Stoyanova, Radka S; Punnen, Sanoj; Ong, Kaye; Buerki, Christine; Aranes, Maria; Kolisnik, Tyler; Margrave, Jennifer; Yousefi, Kasra; Choeurng, Voleak; Davicioni, Elai; Trock, Bruce J; Kane, Christopher J; Pollack, Alan; Davis, John W; Feng, Felix Y; Klein, Eric A

Nguyen, Paul L; Haddad, Zaid; Ross, Ashley E; Martin, Neil E; Deheshi, Samineh; Lam, Lucia L C; Chelliserry, Jijumon; Tosoian, Jeffrey J; Lotan, Tamara L; Spratt, Daniel E; Stoyanova, Radka S; Punnen, Sanoj; Ong, Kaye; Buerki, Christine; Aranes, Maria; Kolisnik, Tyler; Margrave, Jennifer; Yousefi, Kasra; Choeurng, Voleak; Davicioni, Elai; Trock, Bruce J; Kane, Christopher J; Pollack, Alan; Davis, John W; Feng, Felix Y; Klein, Eric A.

Afiliación

Nguyen PL; Department of Radiation Oncology, Dana-Farber/Brigham and Women's Cancer Center and Harvard Medical School, Boston, MA, USA. Electronic address: pnguyen@lroc.harvard.edu.
Haddad Z; GenomeDx Biosciences Inc., Vancouver, BC, Canada.
Ross AE; James Buchanan Brady Urological Institute, Johns Hopkins Hospital, Baltimore, MD, USA.
Martin NE; Department of Radiation Oncology, Dana-Farber/Brigham and Women's Cancer Center and Harvard Medical School, Boston, MA, USA.
Deheshi S; GenomeDx Biosciences Inc., Vancouver, BC, Canada.
Lam LLC; GenomeDx Biosciences Inc., Vancouver, BC, Canada.
Chelliserry J; GenomeDx Biosciences Inc., Vancouver, BC, Canada.
Tosoian JJ; James Buchanan Brady Urological Institute, Johns Hopkins Hospital, Baltimore, MD, USA.
Lotan TL; James Buchanan Brady Urological Institute, Johns Hopkins Hospital, Baltimore, MD, USA.
Spratt DE; Department of Radiation Oncology, Michigan Center for Translational Pathology, Comprehensive Cancer Center, University of Michigan, Ann Arbor, MI, USA.
Stoyanova RS; Department of Radiation Oncology, Miller School of Medicine University of Miami, Miami, FL, USA.
Punnen S; Department of Radiation Oncology, Miller School of Medicine University of Miami, Miami, FL, USA.
Ong K; GenomeDx Biosciences Inc., Vancouver, BC, Canada.
Buerki C; GenomeDx Biosciences Inc., Vancouver, BC, Canada.
Aranes M; GenomeDx Biosciences Inc., Vancouver, BC, Canada.
Kolisnik T; GenomeDx Biosciences Inc., Vancouver, BC, Canada.
Margrave J; GenomeDx Biosciences Inc., Vancouver, BC, Canada.
Yousefi K; GenomeDx Biosciences Inc., Vancouver, BC, Canada.
Choeurng V; GenomeDx Biosciences Inc., Vancouver, BC, Canada.
Davicioni E; GenomeDx Biosciences Inc., Vancouver, BC, Canada.
Trock BJ; James Buchanan Brady Urological Institute, Johns Hopkins Hospital, Baltimore, MD, USA.
Kane CJ; Department of Urology, University of California, San Diego, San Diego, CA, USA.
Pollack A; Department of Radiation Oncology, Miller School of Medicine University of Miami, Miami, FL, USA.
Davis JW; Department of Urology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Feng FY; Department of Radiation Oncology, University of California at San Francisco, San Francisco, CA, USA.
Klein EA; Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH, USA.

Eur Urol ; 72(5): 845-852, 2017 11.

Article en En | MEDLINE | ID: mdl-28528811

Asunto(s)

Antagonistas de Andrógenos/uso terapéutico; Biomarcadores de Tumor/genética; Quimioradioterapia; Perfilación de la Expresión Génica/métodos; Prostatectomía; Neoplasias de la Próstata/genética; Neoplasias de la Próstata/terapia; Anciano; Antagonistas de Andrógenos/efectos adversos; Biopsia con Aguja; Neoplasias Óseas/diagnóstico por imagen; Neoplasias Óseas/genética; Neoplasias Óseas/secundario; Quimioradioterapia/efectos adversos; Quimioradioterapia/mortalidad; Bases de Datos Factuales; Estudios de Factibilidad; Predisposición Genética a la Enfermedad; Humanos; Masculino; Persona de Mediana Edad; Análisis Multivariante; Fenotipo; Valor Predictivo de las Pruebas; Modelos de Riesgos Proporcionales; Prostatectomía/efectos adversos; Prostatectomía/mortalidad; Neoplasias de la Próstata/mortalidad; Neoplasias de la Próstata/patología; Factores de Riesgo; Centros de Atención Terciaria; Factores de Tiempo; Transcriptoma; Resultado del Tratamiento; Estados Unidos

Palabras clave

Biopsy; Genomics; Metastasis; Prostate cancer-specific mortality

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Prostatectomía / Neoplasias de la Próstata / Biomarcadores de Tumor / Perfilación de la Expresión Génica / Quimioradioterapia / Antagonistas de Andrógenos Tipo de estudio: Clinical_trials / Etiology_studies / Evaluation_studies / Prognostic_studies / Risk_factors_studies Límite: Aged / Humans / Male / Middle aged País/Región como asunto: America do norte Idioma: En Revista: Eur Urol Año: 2017 Tipo del documento: Article

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