Remodeling of repolarization and arrhythmia susceptibility in a myosin-binding protein C knockout mouse model.

Toib, Amir; Zhang, Chen; Borghetti, Giulia; Zhang, Xiaoxiao; Wallner, Markus; Yang, Yijun; Troupes, Constantine D; Kubo, Hajime; Sharp, Thomas E; Feldsott, Eric; Berretta, Remus M; Zalavadia, Neil; Trappanese, Danielle M; Harper, Shavonn; Gross, Polina; Chen, Xiongwen; Mohsin, Sadia; Houser, Steven R

Toib, Amir; Zhang, Chen; Borghetti, Giulia; Zhang, Xiaoxiao; Wallner, Markus; Yang, Yijun; Troupes, Constantine D; Kubo, Hajime; Sharp, Thomas E; Feldsott, Eric; Berretta, Remus M; Zalavadia, Neil; Trappanese, Danielle M; Harper, Shavonn; Gross, Polina; Chen, Xiongwen; Mohsin, Sadia; Houser, Steven R.

Afiliación

Toib A; Section of Pediatric Cardiology, St. Christopher's Hospital for Children and Department of Pediatrics, Drexel University College of Medicine, Philadelphia, Pennsylvania; and.
Zhang C; Cardiovascular Research Center and Department of Physiology, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania.
Borghetti G; Cardiovascular Research Center and Department of Physiology, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania.
Zhang X; Cardiovascular Research Center and Department of Physiology, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania.
Wallner M; Cardiovascular Research Center and Department of Physiology, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania.
Yang Y; Cardiovascular Research Center and Department of Physiology, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania.
Troupes CD; Cardiovascular Research Center and Department of Physiology, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania.
Kubo H; Cardiovascular Research Center and Department of Physiology, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania.
Sharp TE; Cardiovascular Research Center and Department of Physiology, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania.
Feldsott E; Cardiovascular Research Center and Department of Physiology, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania.
Berretta RM; Cardiovascular Research Center and Department of Physiology, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania.
Zalavadia N; Cardiovascular Research Center and Department of Physiology, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania.
Trappanese DM; Cardiovascular Research Center and Department of Physiology, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania.
Harper S; Cardiovascular Research Center and Department of Physiology, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania.
Gross P; Cardiovascular Research Center and Department of Physiology, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania.
Chen X; Cardiovascular Research Center and Department of Physiology, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania.
Mohsin S; Cardiovascular Research Center and Department of Physiology, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania.
Houser SR; Cardiovascular Research Center and Department of Physiology, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania.

Am J Physiol Heart Circ Physiol ; 313(3): H620-H630, 2017 Sep 01.

Article en En | MEDLINE | ID: mdl-28646025

Asunto(s)

Proteínas Portadoras/metabolismo; Frecuencia Cardíaca; Miocitos Cardíacos/metabolismo; Canales de Potasio/metabolismo; Potasio/metabolismo; Taquicardia Ventricular/metabolismo; Complejos Prematuros Ventriculares/metabolismo; Potenciales de Acción; Animales; Cardiomegalia/genética; Cardiomegalia/metabolismo; Cardiomegalia/patología; Proteínas Portadoras/genética; Modelos Animales de Enfermedad; Electrocardiografía Ambulatoria; Fibrosis; Predisposición Genética a la Enfermedad; Cinética; Masculino; Ratones de la Cepa 129; Ratones Noqueados; Contracción Miocárdica; Miocitos Cardíacos/patología; Técnicas de Placa-Clamp; Fenotipo; Canales de Potasio/genética; ARN Mensajero/genética; ARN Mensajero/metabolismo; Taquicardia Ventricular/genética; Taquicardia Ventricular/patología; Taquicardia Ventricular/fisiopatología; Telemetría; Complejos Prematuros Ventriculares/genética; Complejos Prematuros Ventriculares/patología; Complejos Prematuros Ventriculares/fisiopatología

Palabras clave

K+ channels; arrhythmia; cardiomyopathy; myosin-binding protein C; repolarization

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Potasio / Canales de Potasio / Proteínas Portadoras / Taquicardia Ventricular / Complejos Prematuros Ventriculares / Miocitos Cardíacos / Frecuencia Cardíaca Límite: Animals Idioma: En Revista: Am J Physiol Heart Circ Physiol Asunto de la revista: CARDIOLOGIA / FISIOLOGIA Año: 2017 Tipo del documento: Article

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google