The minor alleles HCP5 rs3099844 A and PSORS1C1 rs3131003 G are associated with allopurinol-induced severe cutaneous adverse reactions in Han Chinese: a multicentre retrospective case-control clinical study.

Cheng, L; Sun, B; Xiong, Y; Hu, L; Gao, L; Lv, Q; Zhou, M; Li, J; Chen, X; Zhang, W; Zhou, H-H

Cheng, L; Sun, B; Xiong, Y; Hu, L; Gao, L; Lv, Q; Zhou, M; Li, J; Chen, X; Zhang, W; Zhou, H-H.

Afiliación

Cheng L; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Centre, Sun Yat-sen University, Guangzhou, 510060, China.
Sun B; Department of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha, 410008, China.
Xiong Y; Institute of Clinical Pharmacology, Hunan Key Laboratory of Pharmacogenetics, Central South University, Changsha, 410078, China.
Hu L; Department of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha, 410008, China.
Gao L; Institute of Clinical Pharmacology, Hunan Key Laboratory of Pharmacogenetics, Central South University, Changsha, 410078, China.
Lv Q; Department of Pharmacy, Peking University People's Hospital, Beijing, 100044, China.
Zhou M; Department of Pharmacy, Department of Oncology, Cancer Institute, Changsha Central Hospital, Changsha, 410004, China.
Li J; Department of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha, 410008, China.
Chen X; Institute of Clinical Pharmacology, Hunan Key Laboratory of Pharmacogenetics, Central South University, Changsha, 410078, China.
Zhang W; Department of Dermatology, Xiangya Hospital, Central South University, Changsha, 410008, China.
Zhou HH; Department of Dermatology, Xiangya Hospital, Central South University, Changsha, 410008, China.

Br J Dermatol ; 178(3): e191-e193, 2018 03.

Article en En | MEDLINE | ID: mdl-29193002

Asunto(s)

Alopurinol/efectos adversos; Erupciones por Medicamentos/genética; Supresores de la Gota/efectos adversos; Proteínas/genética; ARN Largo no Codificante/genética; Alelos; Pueblo Asiatico/genética; Estudios de Casos y Controles; Femenino; Humanos; Masculino; Polimorfismo de Nucleótido Simple/genética; Estudios Retrospectivos

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas / Alopurinol / Supresores de la Gota / Erupciones por Medicamentos / ARN Largo no Codificante Tipo de estudio: Observational_studies Límite: Female / Humans / Male Idioma: En Revista: Br J Dermatol Año: 2018 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido

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