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An evaluation of the challenges to developing tumor BRCA1 and BRCA2 testing methodologies for clinical practice.
Ellison, Gillian; Ahdesmäki, Miika; Luke, Sally; Waring, Paul M; Wallace, Andrew; Wright, Ronnie; Röthlisberger, Benno; Ludin, Katja; Merkelbach-Bruse, Sabine; Heydt, Carina; Ligtenberg, Marjolijn J L; Mensenkamp, Arjen R; de Castro, David Gonzalez; Jones, Thomas; Vivancos, Ana; Kondrashova, Olga; Pauwels, Patrick; Weyn, Christine; Hahnen, Eric; Hauke, Jan; Soong, Richie; Lai, Zhongwu; Dougherty, Brian; Carr, T Hedley; Johnson, Justin; Mills, John; Barrett, J Carl.
Afiliación
  • Ellison G; Precision Medicine and Genomics, IMED Biotech Unit, AstraZeneca, Macclesfield, UK.
  • Ahdesmäki M; Translational Science, Oncology, IMED Biotech Unit, AstraZeneca, Cambridge, UK.
  • Luke S; R&D Information, AstraZeneca, Cambridge, UK.
  • Waring PM; Department of Pathology, University of Melbourne, Parkville, Melbourne, Victoria, Australia.
  • Wallace A; Genomic Diagnostics Laboratory, Manchester Centre for Genomic Medicine, Central Manchester University Hospitals NHS Foundation Trust, Saint Mary's Hospital, Manchester, UK.
  • Wright R; Genomic Diagnostics Laboratory, Manchester Centre for Genomic Medicine, Central Manchester University Hospitals NHS Foundation Trust, Saint Mary's Hospital, Manchester, UK.
  • Röthlisberger B; Kantonsspital Aarau, Institut für Labormedizin, Abteilung für Medizinische Genetik, Aarau, Switzerland.
  • Ludin K; Kantonsspital Aarau, Institut für Labormedizin, Abteilung für Medizinische Genetik, Aarau, Switzerland.
  • Merkelbach-Bruse S; Institute of Pathology, University Hospital Cologne, Cologne, Germany.
  • Heydt C; Institute of Pathology, University Hospital Cologne, Cologne, Germany.
  • Ligtenberg MJL; Department of Human Genetics, Radboud University Medical Center, Nijmegen, The Netherlands.
  • Mensenkamp AR; Department of Pathology, Radboud University Medical Center, Nijmegen, The Netherlands.
  • de Castro DG; Department of Human Genetics, Radboud University Medical Center, Nijmegen, The Netherlands.
  • Jones T; Centre for Cancer Research and Cell Biology, Queen's University Belfast, Belfast, UK.
  • Vivancos A; The Centre for Molecular Pathology, The Royal Marsden NHS FT, Sutton, UK.
  • Kondrashova O; The Centre for Molecular Pathology, The Royal Marsden NHS FT, Sutton, UK.
  • Pauwels P; Laboratory 2.01, Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain.
  • Weyn C; Department of Pathology, University of Melbourne, Parkville, Melbourne, Victoria, Australia.
  • Hahnen E; Center for Oncological Research (CORE), Pathology Department, University Hospital Antwerp (UZA), Edegem, Belgium.
  • Hauke J; Center for Oncological Research (CORE), Pathology Department, University Hospital Antwerp (UZA), Edegem, Belgium.
  • Soong R; Center for Hereditary Breast and Ovarian Cancer and Center for Integrated Oncology (CIO), Medical Faculty, University Hospital Cologne, Cologne, Germany.
  • Lai Z; Center for Hereditary Breast and Ovarian Cancer and Center for Integrated Oncology (CIO), Medical Faculty, University Hospital Cologne, Cologne, Germany.
  • Dougherty B; Cancer Science Institute of Singapore, and Department of Pathology, National University of Singapore, Singapore, Singapore.
  • Carr TH; Bioscience, Oncology, IMED Biotech Unit, AstraZeneca, IMED Oncology, Waltham, Massachusetts.
  • Johnson J; Translational Science, Oncology, IMED Biotech Unit, AstraZeneca, Waltham, Massachusetts.
  • Mills J; Translational Science, Oncology, IMED Biotech Unit, AstraZeneca, Cambridge, UK.
  • Barrett JC; Translational Science, Oncology, IMED Biotech Unit, AstraZeneca, Waltham, Massachusetts.
Hum Mutat ; 39(3): 394-405, 2018 03.
Article en En | MEDLINE | ID: mdl-29215764
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pautas de la Práctica en Medicina / Pruebas Genéticas / Proteína BRCA1 / Proteína BRCA2 / Neoplasias Tipo de estudio: Evaluation_studies / Guideline / Prognostic_studies Límite: Humans Idioma: En Revista: Hum Mutat Asunto de la revista: GENETICA MEDICA Año: 2018 Tipo del documento: Article País de afiliación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pautas de la Práctica en Medicina / Pruebas Genéticas / Proteína BRCA1 / Proteína BRCA2 / Neoplasias Tipo de estudio: Evaluation_studies / Guideline / Prognostic_studies Límite: Humans Idioma: En Revista: Hum Mutat Asunto de la revista: GENETICA MEDICA Año: 2018 Tipo del documento: Article País de afiliación: Reino Unido