Targeting of phospho-eIF4E by homoharringtonine eradicates a distinct subset of human acute myeloid leukemia.

Zhou, Hong; Xu, Rong Zhen; Gu, Ying; Shi, Peng Fei; Qian, Shenxian

Zhou, Hong; Xu, Rong Zhen; Gu, Ying; Shi, Peng Fei; Qian, Shenxian.

Afiliación

Zhou H; Department of Hematology, Hangzhou First People's Hospital, Hangzhou, PR China.
Xu RZ; Department of Hematology, Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education, Hangzhou, PR China.
Gu Y; Cancer Institute, Second Affiliated Hospital, School of Medicine, Zhejiang University, Zhejiang, PR China.
Shi PF; Department of Hematology, Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education, Hangzhou, PR China.
Qian S; Cancer Institute, Second Affiliated Hospital, School of Medicine, Zhejiang University, Zhejiang, PR China.

Leuk Lymphoma ; 61(5): 1084-1096, 2020 05.

Article en En | MEDLINE | ID: mdl-29334312

Asunto(s)

Leucemia Mieloide Aguda; Apoptosis; Línea Celular Tumoral; Factor 4E Eucariótico de Iniciación/genética; Homoharringtonina; Humanos; Leucemia Mieloide Aguda/tratamiento farmacológico; Factores de Iniciación de Péptidos

Palabras clave

Phospho-eIF4E; acute myeloid leukemia; homoharringtonine

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Leucemia Mieloide Aguda Límite: Humans Idioma: En Revista: Leuk Lymphoma Asunto de la revista: HEMATOLOGIA / NEOPLASIAS Año: 2020 Tipo del documento: Article Pais de publicación: Estados Unidos

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