Your browser doesn't support javascript.
loading
Considerations for Developing Targeted Therapies in Low-Frequency Molecular Subsets of a Disease.
Schuck, Robert N; Woodcock, Janet; Zineh, Issam; Stein, Peter; Jarow, Jonathan; Temple, Robert; Permutt, Thomas; LaVange, Lisa; Beaver, Julia A; Charlab, Rosane; Blumenthal, Gideon M; Dorff, Sarah E; Leptak, Christopher; Lemery, Steven; Rogers, Hobart; Chowdhury, Badrul; Litwack, E David; Pacanowski, Michael.
Afiliación
  • Schuck RN; Office of Clinical Pharmacology, Office of Translational Sciences, Center for Drug Evaluation and Research, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, USA.
  • Woodcock J; Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, USA.
  • Zineh I; Office of Clinical Pharmacology, Office of Translational Sciences, Center for Drug Evaluation and Research, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, USA.
  • Stein P; Office of New Drugs, Center for Drug Evaluation and Research, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, USA.
  • Jarow J; Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, USA.
  • Temple R; Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, USA.
  • Permutt T; Office of Biostatistics, Office of Translational Sciences, Center for Drug Evaluation and Research, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, USA.
  • LaVange L; Office of Biostatistics, Office of Translational Sciences, Center for Drug Evaluation and Research, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, USA.
  • Beaver JA; Office of New Drugs, Center for Drug Evaluation and Research, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, USA.
  • Charlab R; Office of Clinical Pharmacology, Office of Translational Sciences, Center for Drug Evaluation and Research, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, USA.
  • Blumenthal GM; Office of New Drugs, Center for Drug Evaluation and Research, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, USA.
  • Dorff SE; Office of Clinical Pharmacology, Office of Translational Sciences, Center for Drug Evaluation and Research, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, USA.
  • Leptak C; Office of New Drugs, Center for Drug Evaluation and Research, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, USA.
  • Lemery S; Office of New Drugs, Center for Drug Evaluation and Research, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, USA.
  • Rogers H; Office of Clinical Pharmacology, Office of Translational Sciences, Center for Drug Evaluation and Research, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, USA.
  • Chowdhury B; Office of New Drugs, Center for Drug Evaluation and Research, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, USA.
  • Litwack ED; Office of In Vitro Diagnostics and Radiological Health, Center for Devices and Radiological Health, U.S. Food and Drug Administration, Silver Spring, Maryland, USA.
  • Pacanowski M; Office of Clinical Pharmacology, Office of Translational Sciences, Center for Drug Evaluation and Research, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, USA.
Clin Pharmacol Ther ; 104(2): 282-289, 2018 08.
Article en En | MEDLINE | ID: mdl-29473145
Asunto(s)
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Predisposición Genética a la Enfermedad / Medicina de Precisión / Terapia Molecular Dirigida / Tasa de Mutación / Frecuencia de los Genes Tipo de estudio: Guideline / Prognostic_studies / Risk_factors_studies Límite: Animals / Humans País/Región como asunto: America do norte Idioma: En Revista: Clin Pharmacol Ther Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Predisposición Genética a la Enfermedad / Medicina de Precisión / Terapia Molecular Dirigida / Tasa de Mutación / Frecuencia de los Genes Tipo de estudio: Guideline / Prognostic_studies / Risk_factors_studies Límite: Animals / Humans País/Región como asunto: America do norte Idioma: En Revista: Clin Pharmacol Ther Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos