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Structure-activity relationship study of a series of caspase inhibitors containing γ-amino acid moiety for treatment of cholestatic liver disease.
Mou, Jianfeng; Wu, Songliang; Luo, Zhi; Guo, Fengying; He, Haiying; Wang, Jianhua; Lin, Fusen; Guo, Fengxun; Sun, Jianping; Shen, Liang; Zeng, Minggao; Wang, Chuan; Xu, Deming; Gu, Zhengxian; Tian, Xin; Zhang, Aiming; Xu, Hongjiang; Yang, Ling; Zhang, Xiquan; Li, Jian; Chen, Shuhui.
Afiliación
  • Mou J; WuXi AppTec (Shanghai) Co. Ltd., 288 Fute Zhong Road, Shanghai 200131, China.
  • Wu S; WuXi AppTec (Shanghai) Co. Ltd., 288 Fute Zhong Road, Shanghai 200131, China.
  • Luo Z; WuXi AppTec (Shanghai) Co. Ltd., 288 Fute Zhong Road, Shanghai 200131, China.
  • Guo F; WuXi AppTec (Shanghai) Co. Ltd., 288 Fute Zhong Road, Shanghai 200131, China.
  • He H; WuXi AppTec (Shanghai) Co. Ltd., 288 Fute Zhong Road, Shanghai 200131, China. Electronic address: he_haiying@wuxiapptec.com.
  • Wang J; WuXi AppTec (Shanghai) Co. Ltd., 288 Fute Zhong Road, Shanghai 200131, China.
  • Lin F; WuXi AppTec (Shanghai) Co. Ltd., 288 Fute Zhong Road, Shanghai 200131, China.
  • Guo F; WuXi AppTec (Shanghai) Co. Ltd., 288 Fute Zhong Road, Shanghai 200131, China.
  • Sun J; WuXi AppTec (Shanghai) Co. Ltd., 288 Fute Zhong Road, Shanghai 200131, China.
  • Shen L; WuXi AppTec (Shanghai) Co. Ltd., 288 Fute Zhong Road, Shanghai 200131, China.
  • Zeng M; WuXi AppTec (Shanghai) Co. Ltd., 288 Fute Zhong Road, Shanghai 200131, China.
  • Wang C; WuXi AppTec (Shanghai) Co. Ltd., 288 Fute Zhong Road, Shanghai 200131, China.
  • Xu D; WuXi AppTec (Shanghai) Co. Ltd., 288 Fute Zhong Road, Shanghai 200131, China.
  • Gu Z; WuXi AppTec (Shanghai) Co. Ltd., 288 Fute Zhong Road, Shanghai 200131, China.
  • Tian X; Chia Tai Tianqing Pharmaceutical Group Co. Ltd., Building 9, No. 699-8, Xuanwu Road, Nanjing, Jiangsu 210023, China.
  • Zhang A; Chia Tai Tianqing Pharmaceutical Group Co. Ltd., Building 9, No. 699-8, Xuanwu Road, Nanjing, Jiangsu 210023, China.
  • Xu H; Chia Tai Tianqing Pharmaceutical Group Co. Ltd., Building 9, No. 699-8, Xuanwu Road, Nanjing, Jiangsu 210023, China.
  • Yang L; Chia Tai Tianqing Pharmaceutical Group Co. Ltd., Building 9, No. 699-8, Xuanwu Road, Nanjing, Jiangsu 210023, China.
  • Zhang X; Chia Tai Tianqing Pharmaceutical Group Co. Ltd., Building 9, No. 699-8, Xuanwu Road, Nanjing, Jiangsu 210023, China.
  • Li J; WuXi AppTec (Shanghai) Co. Ltd., 288 Fute Zhong Road, Shanghai 200131, China.
  • Chen S; WuXi AppTec (Shanghai) Co. Ltd., 288 Fute Zhong Road, Shanghai 200131, China.
Bioorg Med Chem Lett ; 28(10): 1874-1878, 2018 06 01.
Article en En | MEDLINE | ID: mdl-29650287
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Inhibidores de Caspasas / Aminoácidos Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Bioorg Med Chem Lett Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2018 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Inhibidores de Caspasas / Aminoácidos Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Bioorg Med Chem Lett Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2018 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido