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Ebola Therapeutic Study and Future Directions.
Lu, Da-Yong; Wu, Hong-Ying; Yarla, Nagendra S; Lu, Ting-Ren; Xu, Bin.
Afiliación
  • Lu DY; School of Life Sciences, Shanghai University, Shanghai, Shanghai 200444, China.
  • Wu HY; College of Science, Shanghai University, Shanghai, Shanghai 200444, China.
  • Yarla NS; GITAM University, Viskhatnam, AP, India.
  • Lu TR; College of Science, Shanghai University, Shanghai, Shanghai 200444, China.
  • Xu B; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, Shanghai 201203, China.
  • Jian-Ding; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, Shanghai 201203, China.
Infect Disord Drug Targets ; 19(1): 17-29, 2019.
Article en En | MEDLINE | ID: mdl-30101721
The constant Ebola epidemic outbreaks in Africa arisen in waves of panic worldwide. There is a high mortality rate (30-70%) among the Ebola-infected people in virus- stricken areas. Despite these horrors, the medical capabilities against this deadly viral disease were provided by limited therapeutic agents/options. As a result, several patented agents, biotherapies or prophylactic/therapeutic vaccines need to be reviving into the global markets-including patents of small molecular chemicals, short sequences or oligomers of DNA/RNA, linkages of chemicals with bio-molecules, herbal medicine and so on. In addition, the possible mechanisms of action of these therapeutic options are underway. To promote Ebola biomedical study, the multiple characters of Ebola infections-its origin, pathologic progress, genomic changes, therapeutic context and economic considerations are outlined in this review. Finally, a great difference can be expected after these types of efforts.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Antivirales / Vacunas Virales / Fiebre Hemorrágica Ebola / Ebolavirus Límite: Humans País/Región como asunto: Africa Idioma: En Revista: Infect Disord Drug Targets Asunto de la revista: DOENCAS TRANSMISSIVEIS / TERAPIA POR MEDICAMENTOS Año: 2019 Tipo del documento: Article País de afiliación: China Pais de publicación: Emiratos Árabes Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Antivirales / Vacunas Virales / Fiebre Hemorrágica Ebola / Ebolavirus Límite: Humans País/Región como asunto: Africa Idioma: En Revista: Infect Disord Drug Targets Asunto de la revista: DOENCAS TRANSMISSIVEIS / TERAPIA POR MEDICAMENTOS Año: 2019 Tipo del documento: Article País de afiliación: China Pais de publicación: Emiratos Árabes Unidos