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Synthesis and SAR of new isoxazole-triazole bis-heterocyclic compounds as analogues of natural lignans with antiparasitic activity.
Zimmermann, Lara A; de Moraes, Milene H; da Rosa, Rafael; de Melo, Eduardo B; Paula, Fávero R; Schenkel, Eloir P; Steindel, Mario; Bernardes, Lílian S C.
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  • Zimmermann LA; Graduate Program in Pharmacy, Pharmaceutical and Medicinal Chemistry Laboratory, Department of Pharmaceutical Sciences, Federal University of Santa Catarina, Florianópolis 88040-900, SC, Brazil.
  • de Moraes MH; Department of Microbiology, Immunology and Parasitology, Federal University of Santa Catarina, Florianópolis 88040-900, SC, Brazil.
  • da Rosa R; Graduate Program in Pharmacy, Pharmaceutical and Medicinal Chemistry Laboratory, Department of Pharmaceutical Sciences, Federal University of Santa Catarina, Florianópolis 88040-900, SC, Brazil.
  • de Melo EB; Department of Pharmacy, Western Paraná State University, Cascavel 858119-110, PR, Brazil.
  • Paula FR; Course of Pharmacy, Federal University of Pampa, Uruguaiana 97500-970, RS, Brazil.
  • Schenkel EP; Graduate Program in Pharmacy, Pharmaceutical and Medicinal Chemistry Laboratory, Department of Pharmaceutical Sciences, Federal University of Santa Catarina, Florianópolis 88040-900, SC, Brazil.
  • Steindel M; Department of Microbiology, Immunology and Parasitology, Federal University of Santa Catarina, Florianópolis 88040-900, SC, Brazil.
  • Bernardes LSC; Graduate Program in Pharmacy, Pharmaceutical and Medicinal Chemistry Laboratory, Department of Pharmaceutical Sciences, Federal University of Santa Catarina, Florianópolis 88040-900, SC, Brazil. Electronic address: l.bernardes@ufsc.br.
Bioorg Med Chem ; 26(17): 4850-4862, 2018 09 15.
Article en En | MEDLINE | ID: mdl-30173929
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Trypanosoma cruzi / Lignanos / Leishmania / Antiprotozoarios Tipo de estudio: Qualitative_research Límite: Humans Idioma: En Revista: Bioorg Med Chem Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2018 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Trypanosoma cruzi / Lignanos / Leishmania / Antiprotozoarios Tipo de estudio: Qualitative_research Límite: Humans Idioma: En Revista: Bioorg Med Chem Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2018 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Reino Unido