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A Novel BaEVRless-Pseudotyped γ-Globin Lentiviral Vector Drives High and Stable Fetal Hemoglobin Expression and Improves Thalassemic Erythropoiesis In Vitro.
Drakopoulou, Ekati; Georgomanoli, Maria; Lederer, Carsten W; Kleanthous, Marina; Costa, Caroline; Bernadin, Ornellie; Cosset, François-Loïc; Voskaridou, Ersi; Verhoeyen, Els; Papanikolaou, Eleni; Anagnou, Nicholas P.
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  • Drakopoulou E; 1 Laboratory of Cell and Gene Therapy, Centre for Basic Research, Biomedical Research Foundation of the Academy of Athens (BRFAA), Athens, Greece.
  • Georgomanoli M; 2 Laboratory of Biology, University of Athens School of Medicine, Athens, Greece.
  • Lederer CW; 1 Laboratory of Cell and Gene Therapy, Centre for Basic Research, Biomedical Research Foundation of the Academy of Athens (BRFAA), Athens, Greece.
  • Kleanthous M; 2 Laboratory of Biology, University of Athens School of Medicine, Athens, Greece.
  • Costa C; 3 Department of Molecular Genetics Thalassemia, The Cyprus Institute of Neurology and Genetics, Nicosia, Cyprus.
  • Bernadin O; 4 Cyprus School of Molecular Medicine, Nicosia, Cyprus.
  • Cosset FL; 3 Department of Molecular Genetics Thalassemia, The Cyprus Institute of Neurology and Genetics, Nicosia, Cyprus.
  • Voskaridou E; 4 Cyprus School of Molecular Medicine, Nicosia, Cyprus.
  • Verhoeyen E; 5 CIRI-International Center for Infectiology Research, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR 5308, Ecole Normale Supérieure de Lyon, Lyon, France.
  • Papanikolaou E; 5 CIRI-International Center for Infectiology Research, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR 5308, Ecole Normale Supérieure de Lyon, Lyon, France.
  • Anagnou NP; 5 CIRI-International Center for Infectiology Research, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR 5308, Ecole Normale Supérieure de Lyon, Lyon, France.
Hum Gene Ther ; 30(5): 601-617, 2019 05.
Article en En | MEDLINE | ID: mdl-30324804
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Expresión Génica / Talasemia beta / Lentivirus / Transgenes / Eritropoyesis / Gamma-Globinas / Vectores Genéticos Límite: Humans Idioma: En Revista: Hum Gene Ther Asunto de la revista: GENETICA MEDICA / TERAPEUTICA Año: 2019 Tipo del documento: Article País de afiliación: Grecia Pais de publicación: Estados Unidos
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Expresión Génica / Talasemia beta / Lentivirus / Transgenes / Eritropoyesis / Gamma-Globinas / Vectores Genéticos Límite: Humans Idioma: En Revista: Hum Gene Ther Asunto de la revista: GENETICA MEDICA / TERAPEUTICA Año: 2019 Tipo del documento: Article País de afiliación: Grecia Pais de publicación: Estados Unidos