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IL-2 and IL-15 blockade by BNZ-1, an inhibitor of selective γ-chain cytokines, decreases leukemic T-cell viability.
Wang, T Tiffany; Yang, Jun; Zhang, Yong; Zhang, Meili; Dubois, Sigrid; Conlon, Kevin C; Tagaya, Yutaka; Hamele, Cait E; Dighe, Shubha; Olson, Thomas L; Feith, David J; Azimi, Nazli; Waldmann, Thomas A; Loughran, Thomas P.
Afiliación
  • Wang TT; University of Virginia Cancer Center and Department of Medicine, Division of Hematology & Oncology, University of Virginia School of Medicine, Charlottesville, VA, 22908, USA.
  • Yang J; University of Virginia Cancer Center and Department of Medicine, Division of Hematology & Oncology, University of Virginia School of Medicine, Charlottesville, VA, 22908, USA.
  • Zhang Y; Lymphoid Malignancies Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.
  • Zhang M; Lymphoid Malignancies Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.
  • Dubois S; Laboratory Animal Science Program, Leidos Biomedical Research, Inc., Frederick, MD, 21702, USA.
  • Conlon KC; Lymphoid Malignancies Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.
  • Tagaya Y; Lymphoid Malignancies Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.
  • Hamele CE; BIONIZ Therapeutics, Irvine, CA, 92618, USA.
  • Dighe S; Cell Biology Laboratory, Division of Basic Science, Institute of Human Virology, University of Maryland School of Medicine, Baltimore, MD, 21201, USA.
  • Olson TL; University of Virginia Cancer Center and Department of Medicine, Division of Hematology & Oncology, University of Virginia School of Medicine, Charlottesville, VA, 22908, USA.
  • Feith DJ; University of Virginia Cancer Center and Department of Medicine, Division of Hematology & Oncology, University of Virginia School of Medicine, Charlottesville, VA, 22908, USA.
  • Azimi N; University of Virginia Cancer Center and Department of Medicine, Division of Hematology & Oncology, University of Virginia School of Medicine, Charlottesville, VA, 22908, USA.
  • Waldmann TA; University of Virginia Cancer Center and Department of Medicine, Division of Hematology & Oncology, University of Virginia School of Medicine, Charlottesville, VA, 22908, USA.
  • Loughran TP; BIONIZ Therapeutics, Irvine, CA, 92618, USA.
Leukemia ; 33(5): 1243-1255, 2019 05.
Article en En | MEDLINE | ID: mdl-30353031
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Benzodiazepinas / Supervivencia Celular / Interleucina-2 / Interleucina-15 Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Leukemia Asunto de la revista: HEMATOLOGIA / NEOPLASIAS Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Benzodiazepinas / Supervivencia Celular / Interleucina-2 / Interleucina-15 Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Leukemia Asunto de la revista: HEMATOLOGIA / NEOPLASIAS Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido