The prevalence, clinical status and genotype of cystic fibrosis patients living in Cuba using national registry data.
J Cyst Fibros
; 18(4): 522-524, 2019 07.
Article
en En
| MEDLINE
| ID: mdl-30366848
BACKGROUND: We aimed to establish a national cystic fibrosis (CF) registry for Cuba, a developing country. METHODS: Regional centres that deliver care for all CF patients provided information for a national database. FINDINGS: The prevalence of CF in Cuba is 26.3 cases per 1,000,000 population. The median age at diagnosis is 2â¯years, and the median age of the total population was 15â¯years. Of those aged 16â¯years or older, the prevalence of Pseudomonas aeruginosa infection was 46%, the prevalence of Staphylococcus aureus infection was 36%, and 80% of individuals were receiving oral azithromycin. The commonest gene mutation was F508del which was observed in 50% of patients. INTERPRETATION: These data demonstrate that it is possible to establish a national CF registry in a developing country such as Cuba. This provides baseline data to permit evaluation of health care delivery enable the spread of good clinical practice nationally.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Fibrosis Quística
Tipo de estudio:
Diagnostic_studies
/
Prevalence_studies
/
Risk_factors_studies
Límite:
Adolescent
/
Adult
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Child
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Child, preschool
/
Female
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Humans
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Infant
/
Male
País/Región como asunto:
Caribe
/
Cuba
Idioma:
En
Revista:
J Cyst Fibros
Año:
2019
Tipo del documento:
Article
Pais de publicación:
Países Bajos