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Druggability Simulations and X-Ray Crystallography Reveal a Ligand-Binding Site in the GluA3 AMPA Receptor N-Terminal Domain.
Lee, Ji Young; Krieger, James; Herguedas, Beatriz; García-Nafría, Javier; Dutta, Anindita; Shaikh, Saher A; Greger, Ingo H; Bahar, Ivet.
Afiliación
  • Lee JY; Department of Computational and Systems Biology, School of Medicine, University of Pittsburgh, 3501 Fifth Avenue, Suite 3064 BST3, Pittsburgh, PA 15260, USA.
  • Krieger J; Department of Computational and Systems Biology, School of Medicine, University of Pittsburgh, 3501 Fifth Avenue, Suite 3064 BST3, Pittsburgh, PA 15260, USA.
  • Herguedas B; Neurobiology Division, MRC Laboratory of Molecular Biology, Cambridge Biomedical Campus, Francis Crick Avenue, Cambridge CB2 0QH, UK.
  • García-Nafría J; Neurobiology Division, MRC Laboratory of Molecular Biology, Cambridge Biomedical Campus, Francis Crick Avenue, Cambridge CB2 0QH, UK.
  • Dutta A; Department of Computational and Systems Biology, School of Medicine, University of Pittsburgh, 3501 Fifth Avenue, Suite 3064 BST3, Pittsburgh, PA 15260, USA.
  • Shaikh SA; Neurobiology Division, MRC Laboratory of Molecular Biology, Cambridge Biomedical Campus, Francis Crick Avenue, Cambridge CB2 0QH, UK.
  • Greger IH; Neurobiology Division, MRC Laboratory of Molecular Biology, Cambridge Biomedical Campus, Francis Crick Avenue, Cambridge CB2 0QH, UK. Electronic address: ig@mrc-lmb.cam.ac.uk.
  • Bahar I; Department of Computational and Systems Biology, School of Medicine, University of Pittsburgh, 3501 Fifth Avenue, Suite 3064 BST3, Pittsburgh, PA 15260, USA. Electronic address: bahar@pitt.edu.
Structure ; 27(2): 241-252.e3, 2019 02 05.
Article en En | MEDLINE | ID: mdl-30528594
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Receptores AMPA Límite: Humans Idioma: En Revista: Structure Asunto de la revista: BIOLOGIA MOLECULAR / BIOQUIMICA / BIOTECNOLOGIA Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Receptores AMPA Límite: Humans Idioma: En Revista: Structure Asunto de la revista: BIOLOGIA MOLECULAR / BIOQUIMICA / BIOTECNOLOGIA Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos