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Overexpression of plasmepsin II and plasmepsin III does not directly cause reduction in Plasmodium falciparum sensitivity to artesunate, chloroquine and piperaquine.
Loesbanluechai, Duangkamon; Kotanan, Namfon; de Cozar, Cristina; Kochakarn, Theerarat; Ansbro, Megan R; Chotivanich, Kesinee; White, Nicholas J; Wilairat, Prapon; Lee, Marcus C S; Gamo, Francisco Javier; Sanz, Laura Maria; Chookajorn, Thanat; Kümpornsin, Krittikorn.
Afiliación
  • Loesbanluechai D; Genomics and Evolutionary Medicine Unit (GEM), Centre of Excellence in Malaria Research, Faculty of Tropical Medicine, Mahidol University, Bangkok, 10400, Thailand; Molecular Medicine Program, Multidisciplinary Unit, Faculty of Science, Mahidol University, Bangkok, 10400, Thailand.
  • Kotanan N; Genomics and Evolutionary Medicine Unit (GEM), Centre of Excellence in Malaria Research, Faculty of Tropical Medicine, Mahidol University, Bangkok, 10400, Thailand.
  • de Cozar C; Tres Cantos Medicine Development Campus, GlaxoSmithKline, Parque Tecnológico de Madrid, Tres Cantos, 28760, Spain.
  • Kochakarn T; Genomics and Evolutionary Medicine Unit (GEM), Centre of Excellence in Malaria Research, Faculty of Tropical Medicine, Mahidol University, Bangkok, 10400, Thailand.
  • Ansbro MR; Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD, 20852, USA; Parasites and Microbes Programme, Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, CB10 1SA, United Kingdom.
  • Chotivanich K; Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, 10400, Thailand; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, 10400, Thailand.
  • White NJ; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, 10400, Thailand; Centre for Tropical Medicine and Global Health, Nuffield Department of Clinical Medicine, Churchill Hospital, Oxford, OX3 7LJ, United Kingdom.
  • Wilairat P; Department of Biochemistry, Faculty of Science, Mahidol University, Bangkok, 10400, Thailand.
  • Lee MCS; Parasites and Microbes Programme, Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, CB10 1SA, United Kingdom.
  • Gamo FJ; Tres Cantos Medicine Development Campus, GlaxoSmithKline, Parque Tecnológico de Madrid, Tres Cantos, 28760, Spain.
  • Sanz LM; Tres Cantos Medicine Development Campus, GlaxoSmithKline, Parque Tecnológico de Madrid, Tres Cantos, 28760, Spain.
  • Chookajorn T; Genomics and Evolutionary Medicine Unit (GEM), Centre of Excellence in Malaria Research, Faculty of Tropical Medicine, Mahidol University, Bangkok, 10400, Thailand. Electronic address: thanat.cho@mahidol.edu.
  • Kümpornsin K; Parasites and Microbes Programme, Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, CB10 1SA, United Kingdom. Electronic address: kk11@sanger.ac.uk.
Int J Parasitol Drugs Drug Resist ; 9: 16-22, 2019 04.
Article en En | MEDLINE | ID: mdl-30580023
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Plasmodium falciparum / Quinolinas / Proteínas Protozoarias / Cloroquina / Ácido Aspártico Endopeptidasas / Artesunato / Antimaláricos Tipo de estudio: Diagnostic_studies País/Región como asunto: Asia Idioma: En Revista: Int J Parasitol Drugs Drug Resist Año: 2019 Tipo del documento: Article País de afiliación: Tailandia Pais de publicación: Países Bajos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Plasmodium falciparum / Quinolinas / Proteínas Protozoarias / Cloroquina / Ácido Aspártico Endopeptidasas / Artesunato / Antimaláricos Tipo de estudio: Diagnostic_studies País/Región como asunto: Asia Idioma: En Revista: Int J Parasitol Drugs Drug Resist Año: 2019 Tipo del documento: Article País de afiliación: Tailandia Pais de publicación: Países Bajos