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A chemical biology screen identifies a vulnerability of neuroendocrine cancer cells to SQLE inhibition.
Mahoney, Christopher E; Pirman, David; Chubukov, Victor; Sleger, Taryn; Hayes, Sebastian; Fan, Zi Peng; Allen, Eric L; Chen, Ying; Huang, Lingling; Liu, Meina; Zhang, Yingjia; McDonald, Gabrielle; Narayanaswamy, Rohini; Choe, Sung; Chen, Yue; Gross, Stefan; Cianchetta, Giovanni; Padyana, Anil K; Murray, Stuart; Liu, Wei; Marks, Kevin M; Murtie, Joshua; Dorsch, Marion; Jin, Shengfang; Nagaraja, Nelamangala; Biller, Scott A; Roddy, Thomas; Popovici-Muller, Janeta; Smolen, Gromoslaw A.
Afiliación
  • Mahoney CE; Agios Pharmaceuticals, 88 Sidney Street, Cambridge, MA, 02139, USA.
  • Pirman D; Agios Pharmaceuticals, 88 Sidney Street, Cambridge, MA, 02139, USA.
  • Chubukov V; Agios Pharmaceuticals, 88 Sidney Street, Cambridge, MA, 02139, USA.
  • Sleger T; Agios Pharmaceuticals, 88 Sidney Street, Cambridge, MA, 02139, USA.
  • Hayes S; Agios Pharmaceuticals, 88 Sidney Street, Cambridge, MA, 02139, USA.
  • Fan ZP; Agios Pharmaceuticals, 88 Sidney Street, Cambridge, MA, 02139, USA.
  • Allen EL; Agios Pharmaceuticals, 88 Sidney Street, Cambridge, MA, 02139, USA.
  • Chen Y; Shanghai ChemPartner Co. Ltd., 998 Halei Road, Pudong, 201203, Shanghai, China.
  • Huang L; Shanghai ChemPartner Co. Ltd., 998 Halei Road, Pudong, 201203, Shanghai, China.
  • Liu M; Shanghai ChemPartner Co. Ltd., 998 Halei Road, Pudong, 201203, Shanghai, China.
  • Zhang Y; Shanghai ChemPartner Co. Ltd., 998 Halei Road, Pudong, 201203, Shanghai, China.
  • McDonald G; Agios Pharmaceuticals, 88 Sidney Street, Cambridge, MA, 02139, USA.
  • Narayanaswamy R; Agios Pharmaceuticals, 88 Sidney Street, Cambridge, MA, 02139, USA.
  • Choe S; Agios Pharmaceuticals, 88 Sidney Street, Cambridge, MA, 02139, USA.
  • Chen Y; Agios Pharmaceuticals, 88 Sidney Street, Cambridge, MA, 02139, USA.
  • Gross S; Agios Pharmaceuticals, 88 Sidney Street, Cambridge, MA, 02139, USA.
  • Cianchetta G; Agios Pharmaceuticals, 88 Sidney Street, Cambridge, MA, 02139, USA.
  • Padyana AK; Agios Pharmaceuticals, 88 Sidney Street, Cambridge, MA, 02139, USA.
  • Murray S; Agios Pharmaceuticals, 88 Sidney Street, Cambridge, MA, 02139, USA.
  • Liu W; Agios Pharmaceuticals, 88 Sidney Street, Cambridge, MA, 02139, USA.
  • Marks KM; Agios Pharmaceuticals, 88 Sidney Street, Cambridge, MA, 02139, USA.
  • Murtie J; Agios Pharmaceuticals, 88 Sidney Street, Cambridge, MA, 02139, USA.
  • Dorsch M; Agios Pharmaceuticals, 88 Sidney Street, Cambridge, MA, 02139, USA.
  • Jin S; Agios Pharmaceuticals, 88 Sidney Street, Cambridge, MA, 02139, USA.
  • Nagaraja N; Agios Pharmaceuticals, 88 Sidney Street, Cambridge, MA, 02139, USA.
  • Biller SA; Agios Pharmaceuticals, 88 Sidney Street, Cambridge, MA, 02139, USA.
  • Roddy T; Agios Pharmaceuticals, 88 Sidney Street, Cambridge, MA, 02139, USA.
  • Popovici-Muller J; Agios Pharmaceuticals, 88 Sidney Street, Cambridge, MA, 02139, USA.
  • Smolen GA; Decibel Therapeutics, 1325 Boylston Street, Suite 500, Boston, MA, 02215, USA.
Nat Commun ; 10(1): 96, 2019 01 09.
Article en En | MEDLINE | ID: mdl-30626880
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ensayos de Selección de Medicamentos Antitumorales / Sistemas de Liberación de Medicamentos / Escualeno-Monooxigenasa / Antineoplásicos Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Añadir a Mi BVS
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XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ensayos de Selección de Medicamentos Antitumorales / Sistemas de Liberación de Medicamentos / Escualeno-Monooxigenasa / Antineoplásicos Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos