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Can acetylcysteine ameliorate cisplatin-induced toxicities and oxidative stress without decreasing antitumor efficacy? A randomized, double-blind, placebo-controlled trial involving patients with head and neck cancer.
Visacri, Marília B; Quintanilha, Júlia C F; de Sousa, Vanessa M; Amaral, Laís S; de F L Ambrósio, Rosiane; Calonga, Luciane; Curi, Silvia F B B; de T Leme, Mayra F; Chone, Carlos T; Altemani, João M C; Mazzola, Priscila G; Malaguti, Carina; Vercesi, Aníbal E; Lima, Carmen S P; Moriel, Patricia.
Afiliación
  • Visacri MB; School of Medical Sciences, University of Campinas, Campinas, Brazil.
  • Quintanilha JCF; School of Medical Sciences, University of Campinas, Campinas, Brazil.
  • de Sousa VM; Faculty of Pharmaceutical Sciences, University of Campinas, Campinas, Brazil.
  • Amaral LS; School of Medical Sciences, University of Campinas, Campinas, Brazil.
  • de F L Ambrósio R; School of Medical Sciences, University of Campinas, Campinas, Brazil.
  • Calonga L; Clinical Hospital, University of Campinas, Campinas, Brazil.
  • Curi SFBB; Clinical Hospital, University of Campinas, Campinas, Brazil.
  • de T Leme MF; Clinical Hospital, University of Campinas, Campinas, Brazil.
  • Chone CT; Clinical Hospital, University of Campinas, Campinas, Brazil.
  • Altemani JMC; Clinical Hospital, University of Campinas, Campinas, Brazil.
  • Mazzola PG; Faculty of Pharmaceutical Sciences, University of Campinas, Campinas, Brazil.
  • Malaguti C; School of Medical Sciences, University of Campinas, Campinas, Brazil.
  • Vercesi AE; School of Medical Sciences, University of Campinas, Campinas, Brazil.
  • Lima CSP; School of Medical Sciences, University of Campinas, Campinas, Brazil.
  • Moriel P; Faculty of Pharmaceutical Sciences, University of Campinas, Campinas, Brazil.
Cancer Med ; 8(5): 2020-2030, 2019 05.
Article en En | MEDLINE | ID: mdl-30977273
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Acetilcisteína / Cisplatino / Estrés Oxidativo / Efectos Colaterales y Reacciones Adversas Relacionados con Medicamentos / Neoplasias de Cabeza y Cuello Tipo de estudio: Clinical_trials / Prognostic_studies / Risk_factors_studies Límite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Cancer Med Año: 2019 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Estados Unidos
Texto completo
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PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Acetilcisteína / Cisplatino / Estrés Oxidativo / Efectos Colaterales y Reacciones Adversas Relacionados con Medicamentos / Neoplasias de Cabeza y Cuello Tipo de estudio: Clinical_trials / Prognostic_studies / Risk_factors_studies Límite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Cancer Med Año: 2019 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Estados Unidos