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Small-Molecule Modulation of TDP-43 Recruitment to Stress Granules Prevents Persistent TDP-43 Accumulation in ALS/FTD.
Fang, Mark Y; Markmiller, Sebastian; Vu, Anthony Q; Javaherian, Ashkan; Dowdle, William E; Jolivet, Philippe; Bushway, Paul J; Castello, Nicholas A; Baral, Ashmita; Chan, Michelle Y; Linsley, Jeremy W; Linsley, Drew; Mercola, Mark; Finkbeiner, Steven; Lecuyer, Eric; Lewcock, Joseph W; Yeo, Gene W.
Afiliación
  • Fang MY; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093, USA; Stem Cell Program, University of California, San Diego, La Jolla, CA 92093, USA; Institute for Genomic Medicine, University of California, San Diego, La Jolla, CA 92093, USA.
  • Markmiller S; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093, USA; Stem Cell Program, University of California, San Diego, La Jolla, CA 92093, USA; Institute for Genomic Medicine, University of California, San Diego, La Jolla, CA 92093, USA.
  • Vu AQ; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093, USA; Stem Cell Program, University of California, San Diego, La Jolla, CA 92093, USA; Institute for Genomic Medicine, University of California, San Diego, La Jolla, CA 92093, USA.
  • Javaherian A; Gladstone Institutes, San Francisco, CA 94158, USA.
  • Dowdle WE; Denali Therapeutics Inc., South San Francisco, CA 94080, USA.
  • Jolivet P; Institut de Recherches Cliniques de Montréal, Montréal, Québec H2W 1R7, Canada.
  • Bushway PJ; Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037, USA; Department of Bioengineering, University of California, San Diego, La Jolla, CA 92093.
  • Castello NA; Gladstone Institutes, San Francisco, CA 94158, USA.
  • Baral A; Gladstone Institutes, San Francisco, CA 94158, USA.
  • Chan MY; Gladstone Institutes, San Francisco, CA 94158, USA.
  • Linsley JW; Gladstone Institutes, San Francisco, CA 94158, USA.
  • Linsley D; Brown University, Department of Cognitive, Linguistic and Psychological Sciences, Providence, RI 02912, USA.
  • Mercola M; Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037, USA; Department of Bioengineering, University of California, San Diego, La Jolla, CA 92093.
  • Finkbeiner S; Taube/Koret Center for Neurodegenerative Disease Research and DaedalusBio, Gladstone Institutes, San Francisco, CA 94158, USA; Departments of Neurology and Physiology, University of California, San Francisco, San Francisco, CA 94158, USA.
  • Lecuyer E; Institut de Recherches Cliniques de Montréal, Montréal, Québec H2W 1R7, Canada; Département de Biochimie et Médecine Moléculaire, Université de Montréal, Montréal, Québec H3C 3J7, Canada; Division of Experimental Medicine, McGill University, Montréal, Québec H3A 1A3, Canada.
  • Lewcock JW; Denali Therapeutics Inc., South San Francisco, CA 94080, USA.
  • Yeo GW; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093, USA; Stem Cell Program, University of California, San Diego, La Jolla, CA 92093, USA; Institute for Genomic Medicine, University of California, San Diego, La Jolla, CA 92093, USA. Electronic addre
Neuron ; 103(5): 802-819.e11, 2019 09 04.
Article en En | MEDLINE | ID: mdl-31272829
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Estrés Fisiológico / Gránulos Citoplasmáticos / Proteínas de Unión al ADN / Bibliotecas de Moléculas Pequeñas / Demencia Frontotemporal / Agregación Patológica de Proteínas / Esclerosis Amiotrófica Lateral / Neuronas Motoras Límite: Humans Idioma: En Revista: Neuron Asunto de la revista: NEUROLOGIA Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Estrés Fisiológico / Gránulos Citoplasmáticos / Proteínas de Unión al ADN / Bibliotecas de Moléculas Pequeñas / Demencia Frontotemporal / Agregación Patológica de Proteínas / Esclerosis Amiotrófica Lateral / Neuronas Motoras Límite: Humans Idioma: En Revista: Neuron Asunto de la revista: NEUROLOGIA Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos