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The Histone Deacetylase SIRT6 Restrains Transcription Elongation via Promoter-Proximal Pausing.
Etchegaray, Jean-Pierre; Zhong, Lei; Li, Catherine; Henriques, Telmo; Ablondi, Eileen; Nakadai, Tomoyoshi; Van Rechem, Capucine; Ferrer, Christina; Ross, Kenneth N; Choi, Jee-Eun; Samarakkody, Ann; Ji, Fei; Chang, Andrew; Sadreyev, Ruslan I; Ramaswamy, Sridhar; Nechaev, Sergei; Whetstine, Johnathan R; Roeder, Robert G; Adelman, Karen; Goren, Alon; Mostoslavsky, Raul.
Afiliación
  • Etchegaray JP; The Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA 02114, USA. Electronic address: etchegje@newark.rutgers.edu.
  • Zhong L; The Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA 02114, USA.
  • Li C; The Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA 02114, USA.
  • Henriques T; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA.
  • Ablondi E; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA.
  • Nakadai T; Laboratory of Biochemistry and Molecular Biology, The Rockefeller University, New York, NY 10065, USA.
  • Van Rechem C; The Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA 02114, USA.
  • Ferrer C; The Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA 02114, USA.
  • Ross KN; The Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA 02114, USA.
  • Choi JE; The Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA 02114, USA.
  • Samarakkody A; University of North Dakota School of Medicine, Grand Forks, ND 58201, USA.
  • Ji F; Department of Molecular Biology, Massachusetts General Hospital, Boston, MA 02114, USA; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA.
  • Chang A; The Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA 02114, USA.
  • Sadreyev RI; Department of Molecular Biology, Massachusetts General Hospital, Boston, MA 02114, USA; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA; Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.
  • Ramaswamy S; The Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA 02114, USA.
  • Nechaev S; University of North Dakota School of Medicine, Grand Forks, ND 58201, USA.
  • Whetstine JR; The Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA 02114, USA.
  • Roeder RG; Laboratory of Biochemistry and Molecular Biology, The Rockefeller University, New York, NY 10065, USA.
  • Adelman K; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA.
  • Goren A; Department of Medicine, University of California San Diego, La Jolla, CA 92093, USA. Electronic address: agoren@ucsd.edu.
  • Mostoslavsky R; The Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA 02114, USA; The MGH Center for Regenerative Medicine, Harvard Medical School, Boston, MA 02114, USA; The Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA. Electronic address: rmostoslavsky@mgh.harvard.ed
Mol Cell ; 75(4): 683-699.e7, 2019 08 22.
Article en En | MEDLINE | ID: mdl-31399344

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: ARN Polimerasa II / Regiones Promotoras Genéticas / Sirtuinas / Elongación de la Transcripción Genética Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Mol Cell Asunto de la revista: BIOLOGIA MOLECULAR Año: 2019 Tipo del documento: Article Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: ARN Polimerasa II / Regiones Promotoras Genéticas / Sirtuinas / Elongación de la Transcripción Genética Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Mol Cell Asunto de la revista: BIOLOGIA MOLECULAR Año: 2019 Tipo del documento: Article Pais de publicación: Estados Unidos