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Pharmacological inhibition of the MEK5/ERK5 and PI3K/Akt signaling pathways synergistically reduces viability in triple-negative breast cancer.
Wright, Thomas D; Raybuck, Christopher; Bhatt, Akshita; Monlish, Darlene; Chakrabarty, Suravi; Wendekier, Katy; Gartland, Nathan; Gupta, Mohit; Burow, Matthew E; Flaherty, Patrick T; Cavanaugh, Jane E.
Afiliación
  • Wright TD; Department of Pharmacology and Toxicology, Duquesne University, Pittsburgh, Pennsylvania.
  • Raybuck C; Department of Pharmacology and Toxicology, Duquesne University, Pittsburgh, Pennsylvania.
  • Bhatt A; Department of Pharmacology and Toxicology, Duquesne University, Pittsburgh, Pennsylvania.
  • Monlish D; Department of Pharmacology and Toxicology, Duquesne University, Pittsburgh, Pennsylvania.
  • Chakrabarty S; Department of Pediatrics, Washington University in St Louis, St Louis, Missouri.
  • Wendekier K; Department of Medicinal Chemistry, Duquesne University, Pittsburgh, Pennsylvania.
  • Gartland N; Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium.
  • Gupta M; Department of Pharmacology and Toxicology, Duquesne University, Pittsburgh, Pennsylvania.
  • Burow ME; Department of Pharmacology and Toxicology, Duquesne University, Pittsburgh, Pennsylvania.
  • Flaherty PT; Department of Medicinal Chemistry, Duquesne University, Pittsburgh, Pennsylvania.
  • Cavanaugh JE; Department of Medicine, Tulane University School of Medicine, New Orleans, Louisiana.
J Cell Biochem ; 121(2): 1156-1168, 2020 02.
Article en En | MEDLINE | ID: mdl-31464004
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Transducción de Señal / Supervivencia Celular / Fosfatidilinositol 3-Quinasas / MAP Quinasa Quinasa 5 / Proteína Quinasa 7 Activada por Mitógenos / Proteínas Proto-Oncogénicas c-akt / Neoplasias de la Mama Triple Negativas Tipo de estudio: Prognostic_studies Límite: Female / Humans Idioma: En Revista: J Cell Biochem Año: 2020 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Transducción de Señal / Supervivencia Celular / Fosfatidilinositol 3-Quinasas / MAP Quinasa Quinasa 5 / Proteína Quinasa 7 Activada por Mitógenos / Proteínas Proto-Oncogénicas c-akt / Neoplasias de la Mama Triple Negativas Tipo de estudio: Prognostic_studies Límite: Female / Humans Idioma: En Revista: J Cell Biochem Año: 2020 Tipo del documento: Article Pais de publicación: Estados Unidos