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Pancreatic cancer organoids recapitulate disease and allow personalized drug screening.
Driehuis, Else; van Hoeck, Arne; Moore, Kat; Kolders, Sigrid; Francies, Hayley E; Gulersonmez, M Can; Stigter, Edwin C A; Burgering, Boudewijn; Geurts, Veerle; Gracanin, Ana; Bounova, Gergana; Morsink, Folkert H; Vries, Robert; Boj, Sylvia; van Es, Johan; Offerhaus, G Johan A; Kranenburg, Onno; Garnett, Mathew J; Wessels, Lodewyk; Cuppen, Edwin; Brosens, Lodewijk A A; Clevers, Hans.
Afiliación
  • Driehuis E; Oncode Institute, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands.
  • van Hoeck A; Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences and University Medical Center Utrecht, 3584 CT Utrecht, The Netherlands.
  • Moore K; Oncode Institute, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands.
  • Kolders S; Center for Molecular Medicine, University Medical Center Utrecht, 3584 CG Utrecht, The Netherlands.
  • Francies HE; Division of Molecular Carcinogenesis, The Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands.
  • Gulersonmez MC; Oncode Institute, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands.
  • Stigter ECA; Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences and University Medical Center Utrecht, 3584 CT Utrecht, The Netherlands.
  • Burgering B; Wellcome Sanger Institute, Hinxton CB10 1SA, United Kingdom.
  • Geurts V; Department of Molecular Cancer Research, Center Molecular Medicine, Oncode Institute, University Medical Center Utrecht, Utrecht 3584 CM, The Netherlands.
  • Gracanin A; Department of Molecular Cancer Research, Center Molecular Medicine, Oncode Institute, University Medical Center Utrecht, Utrecht 3584 CM, The Netherlands.
  • Bounova G; Department of Molecular Cancer Research, Center Molecular Medicine, Oncode Institute, University Medical Center Utrecht, Utrecht 3584 CM, The Netherlands.
  • Morsink FH; Oncode Institute, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands.
  • Vries R; Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences and University Medical Center Utrecht, 3584 CT Utrecht, The Netherlands.
  • Boj S; Hubrecht Organoid Technology, Utrecht 3584 CM, The Netherlands.
  • van Es J; Division of Molecular Carcinogenesis, The Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands.
  • Offerhaus GJA; Department of Pathology, University Medical Center Utrecht, Utrecht 3584 CM, The Netherlands.
  • Kranenburg O; Hubrecht Organoid Technology, Utrecht 3584 CM, The Netherlands.
  • Garnett MJ; Hubrecht Organoid Technology, Utrecht 3584 CM, The Netherlands.
  • Wessels L; Oncode Institute, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands.
  • Cuppen E; Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences and University Medical Center Utrecht, 3584 CT Utrecht, The Netherlands.
  • Brosens LAA; Department of Pathology, University Medical Center Utrecht, Utrecht 3584 CM, The Netherlands.
  • Clevers H; Utrecht Platform for Organoid Technology, Utrecht Medical Center Utrecht, Utrecht 3584 CM, The Netherlands.
Proc Natl Acad Sci U S A ; 116(52): 26580-26590, 2019 Dec 26.
Article en En | MEDLINE | ID: mdl-31818951

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Diagnostic_studies / Screening_studies Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2019 Tipo del documento: Article País de afiliación: Países Bajos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Diagnostic_studies / Screening_studies Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2019 Tipo del documento: Article País de afiliación: Países Bajos