Methods for Estimating the Probability of Clonality in Cell Line Development.

Chen, Chun; Le, Kim; Le, Huong; Daris, Kristi; Soice, Neil; Stevens, Jennitte; Goudar, Chetan T

Chen, Chun; Le, Kim; Le, Huong; Daris, Kristi; Soice, Neil; Stevens, Jennitte; Goudar, Chetan T.

Afiliación

Chen C; Drug Substance Technologies, Process Development, Amgen Inc., 1 Amgen Center Drive, Thousand Oaks, CA, 91320, USA.
Le K; Drug Substance Technologies, Process Development, Amgen Inc., 1 Amgen Center Drive, Thousand Oaks, CA, 91320, USA.
Le H; Drug Substance Technologies, Process Development, Amgen Inc., 1 Amgen Center Drive, Thousand Oaks, CA, 91320, USA.
Daris K; Drug Substance Technologies, Process Development, Amgen Inc., 1 Amgen Center Drive, Thousand Oaks, CA, 91320, USA.
Soice N; Drug Substance Technologies, Process Development, Amgen Inc., 1 Amgen Center Drive, Thousand Oaks, CA, 91320, USA.
Stevens J; Drug Substance Technologies, Process Development, Amgen Inc., 1 Amgen Center Drive, Thousand Oaks, CA, 91320, USA.
Goudar CT; Drug Substance Technologies, Process Development, Amgen Inc., 1 Amgen Center Drive, Thousand Oaks, CA, 91320, USA.

Biotechnol J ; 15(2): e1900289, 2020 Feb.

Article en En | MEDLINE | ID: mdl-31841273

Asunto(s)

Productos Biológicos/metabolismo; Clonación de Organismos; Animales; Línea Celular; Células Clonales; Industria Farmacéutica; Humanos; Mamíferos

Palabras clave

cell line development; clonality; imaging; limiting dilution; probability of clonality

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Productos Biológicos / Clonación de Organismos Tipo de estudio: Guideline Límite: Animals / Humans Idioma: En Revista: Biotechnol J Asunto de la revista: BIOTECNOLOGIA Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Alemania

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