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Biomarker recommendation for PD-1/PD-L1 immunotherapy development in pediatric cancer based on digital image analysis of PD-L1 and immune cells.
Silva, Manuel A; Triltsch, Nicolas; Leis, Simon; Kanchev, Ivan; Tan, Tze Heng; Van Peel, Benjamine; Van Kerckhoven, Marian; Deschoolmeester, Vanessa; Zimmermann, Johannes.
Afiliación
  • Silva MA; Department of Translational Medicine, Clinical Biomarkers and Companion Diagnostics, Merck KGaA, Darmstadt, Germany.
  • Triltsch N; Department of Image Analysis Professional Services, Definiens GmbH, Munich, Germany.
  • Leis S; Department of Image Analysis Professional Services, Definiens GmbH, Munich, Germany.
  • Kanchev I; Department of Image Analysis Professional Services, Definiens GmbH, Munich, Germany.
  • Tan TH; Department of Image Analysis Professional Services, Definiens GmbH, Munich, Germany.
  • Van Peel B; Department of Clinical Operations and Assay Development, HistoGeneX, Antwerp, Belgium.
  • Van Kerckhoven M; Department of Clinical Operations and Assay Development, HistoGeneX, Antwerp, Belgium.
  • Deschoolmeester V; Department of Clinical Operations and Assay Development, HistoGeneX, Antwerp, Belgium.
  • Zimmermann J; Department of Image Analysis Professional Services, Definiens GmbH, Munich, Germany.
J Pathol Clin Res ; 6(2): 124-137, 2020 04.
Article en En | MEDLINE | ID: mdl-31922656
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Carcinoma de Pulmón de Células no Pequeñas / Antígeno B7-H1 / Receptor de Muerte Celular Programada 1 / Neoplasias Pulmonares Tipo de estudio: Qualitative_research / Risk_factors_studies Límite: Humans Idioma: En Revista: J Pathol Clin Res Año: 2020 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Carcinoma de Pulmón de Células no Pequeñas / Antígeno B7-H1 / Receptor de Muerte Celular Programada 1 / Neoplasias Pulmonares Tipo de estudio: Qualitative_research / Risk_factors_studies Límite: Humans Idioma: En Revista: J Pathol Clin Res Año: 2020 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Reino Unido