Older adults with frailty syndrome present an altered platelet function and an increased level of circulating oxidative stress and mitochondrial dysfunction biomarker GDF-15.

Arauna, Diego; García, Francisco; Rodríguez-Mañas, Leocadio; Marrugat, Jaume; Sáez, Claudia; Alarcón, Marcelo; Wehinger, Sergio; Espinosa-Parrilla, Yolanda; Palomo, Iván; Fuentes, Eduardo

Arauna, Diego; García, Francisco; Rodríguez-Mañas, Leocadio; Marrugat, Jaume; Sáez, Claudia; Alarcón, Marcelo; Wehinger, Sergio; Espinosa-Parrilla, Yolanda; Palomo, Iván; Fuentes, Eduardo.

Afiliación

Arauna D; Thrombosis Research Center, Medical Technology School, Department of Clinical Biochemistry and Immunohaematology, Faculty of Health Sciences, Universidad de Talca, Talca, Chile.
García F; Department of Geriatric Medicine, Complejo Hospitalario de Toledo, Toledo, Spain.
Rodríguez-Mañas L; Division of Geriatrics, Hospital Universitario de Getafe, Getafe, Spain.
Marrugat J; REGICOR Research Group, IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain.
Sáez C; Department of Hematology and Oncology, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.
Alarcón M; Thrombosis Research Center, Medical Technology School, Department of Clinical Biochemistry and Immunohaematology, Faculty of Health Sciences, Universidad de Talca, Talca, Chile.
Wehinger S; Thrombosis Research Center, Medical Technology School, Department of Clinical Biochemistry and Immunohaematology, Faculty of Health Sciences, Universidad de Talca, Talca, Chile.
Espinosa-Parrilla Y; Thematic Task Force on Healthy Aging, CUECH Research Network, Chile; School of Medicine and Laboratory of Molecular Medicine (LMM), Center for Education, Healthcare and Investigation (CADI), Universidad de Magallanes, Punta Arenas, Chile.
Palomo I; Thrombosis Research Center, Medical Technology School, Department of Clinical Biochemistry and Immunohaematology, Faculty of Health Sciences, Universidad de Talca, Talca, Chile; Thematic Task Force on Healthy Aging, CUECH Research Network, Chile. Electronic address: ipalomo@utalca.cl.
Fuentes E; Thrombosis Research Center, Medical Technology School, Department of Clinical Biochemistry and Immunohaematology, Faculty of Health Sciences, Universidad de Talca, Talca, Chile; Thematic Task Force on Healthy Aging, CUECH Research Network, Chile. Electronic address: edfuentes@utalca.cl.

Free Radic Biol Med ; 149: 64-71, 2020 03.

Article en En | MEDLINE | ID: mdl-31926293

Asunto(s)

Fragilidad; Anciano; Biomarcadores; Estudios de Casos y Controles; Anciano Frágil; Fragilidad/diagnóstico; Factor 15 de Diferenciación de Crecimiento; Humanos; Mitocondrias; Estrés Oxidativo

Palabras clave

Aging; Frailty; Mitochondrial dysfunction; Oxidative stress; Platelet

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Fragilidad Tipo de estudio: Diagnostic_studies / Guideline / Observational_studies / Qualitative_research / Risk_factors_studies Límite: Aged / Humans Idioma: En Revista: Free Radic Biol Med Asunto de la revista: BIOQUIMICA / MEDICINA Año: 2020 Tipo del documento: Article País de afiliación: Chile

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google