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Development of a Brigatinib degrader (SIAIS117) as a potential treatment for ALK positive cancer resistance.
Sun, Ning; Ren, Chaowei; Kong, Ying; Zhong, Hui; Chen, Jinju; Li, Yan; Zhang, Jianshui; Zhou, Yuedong; Qiu, Xing; Lin, Haifan; Song, Xiaoling; Yang, Xiaobao; Jiang, Biao.
Afiliación
  • Sun N; Shanghai Institute for Advanced Immunochemical Studies, ShanghaiTech University, 393 Middle Huaxia Road, Shanghai, 201210, China.
  • Ren C; Shanghai Institute for Advanced Immunochemical Studies, ShanghaiTech University, 393 Middle Huaxia Road, Shanghai, 201210, China.
  • Kong Y; Jing Medicine Technology (Shanghai), Ltd., Y building, 230 Haike Road, Shanghai, 201210, China.
  • Zhong H; Shanghai Institute for Advanced Immunochemical Studies, ShanghaiTech University, 393 Middle Huaxia Road, Shanghai, 201210, China; Changzhou University, Changzhou, Jiangsu, 213164, China.
  • Chen J; Jing Medicine Technology (Shanghai), Ltd., Y building, 230 Haike Road, Shanghai, 201210, China.
  • Li Y; Jing Medicine Technology (Shanghai), Ltd., Y building, 230 Haike Road, Shanghai, 201210, China.
  • Zhang J; Jing Medicine Technology (Shanghai), Ltd., Y building, 230 Haike Road, Shanghai, 201210, China.
  • Zhou Y; Jing Medicine Technology (Shanghai), Ltd., Y building, 230 Haike Road, Shanghai, 201210, China.
  • Qiu X; CAS Key Laboratory of Synthetic Chemistry of Natural Substances, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Road, Shanghai, 200032, China.
  • Lin H; Shanghai Institute for Advanced Immunochemical Studies, ShanghaiTech University, 393 Middle Huaxia Road, Shanghai, 201210, China; Yale Stem Cell Center, Yale University, New Haven, CT, 06511, USA. Electronic address: Linhf@shanghaitech.edu.cn.
  • Song X; Shanghai Institute for Advanced Immunochemical Studies, ShanghaiTech University, 393 Middle Huaxia Road, Shanghai, 201210, China. Electronic address: songxl@shanghaitech.edu.cn.
  • Yang X; Shanghai Institute for Advanced Immunochemical Studies, ShanghaiTech University, 393 Middle Huaxia Road, Shanghai, 201210, China. Electronic address: yangxb@shanghaitech.edu.cn.
  • Jiang B; Shanghai Institute for Advanced Immunochemical Studies, ShanghaiTech University, 393 Middle Huaxia Road, Shanghai, 201210, China; CAS Key Laboratory of Synthetic Chemistry of Natural Substances, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Road, Shanghai, 200032
Eur J Med Chem ; 193: 112190, 2020 May 01.
Article en En | MEDLINE | ID: mdl-32179332
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Carcinoma de Pulmón de Células no Pequeñas / Inhibidores de Proteínas Quinasas / Desarrollo de Medicamentos / Quinasa de Linfoma Anaplásico / Neoplasias Pulmonares / Antineoplásicos Límite: Humans Idioma: En Revista: Eur J Med Chem Año: 2020 Tipo del documento: Article País de afiliación: China
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Carcinoma de Pulmón de Células no Pequeñas / Inhibidores de Proteínas Quinasas / Desarrollo de Medicamentos / Quinasa de Linfoma Anaplásico / Neoplasias Pulmonares / Antineoplásicos Límite: Humans Idioma: En Revista: Eur J Med Chem Año: 2020 Tipo del documento: Article País de afiliación: China