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Acquired resistance to DZNep-mediated apoptosis is associated with copy number gains of AHCY in a B-cell lymphoma model.
Akpa, Chidimma Agatha; Kleo, Karsten; Oker, Elisabeth; Tomaszewski, Nancy; Messerschmidt, Clemens; López, Cristina; Wagener, Rabea; Oehl-Huber, Kathrin; Dettmer, Katja; Schoeler, Anne; Lenze, Dido; Oefner, Peter J; Beule, Dieter; Siebert, Reiner; Capper, David; Dimitrova, Lora; Hummel, Michael.
Afiliación
  • Akpa CA; Department of Experimental Hematopathology, Institute of Pathology, Charité Medical University, Berlin, Charitéplatz 1, 10117, Berlin, Germany. chidimma.akpa@charite.de.
  • Kleo K; Berlin School of Integrative Oncology, Charité - Medical University of Berlin, Berlin, Germany. chidimma.akpa@charite.de.
  • Oker E; Department of Experimental Hematopathology, Institute of Pathology, Charité Medical University, Berlin, Charitéplatz 1, 10117, Berlin, Germany.
  • Tomaszewski N; Department of Experimental Hematopathology, Institute of Pathology, Charité Medical University, Berlin, Charitéplatz 1, 10117, Berlin, Germany.
  • Messerschmidt C; Department of Experimental Hematopathology, Institute of Pathology, Charité Medical University, Berlin, Charitéplatz 1, 10117, Berlin, Germany.
  • López C; Berlin Institute of Health, Charité Core Unit Bioinformatics, Berlin, Germany.
  • Wagener R; Institute of Human Genetics, Ulm University and Ulm University Medical Center, Ulm, Germany.
  • Oehl-Huber K; Institute of Human Genetics, Ulm University and Ulm University Medical Center, Ulm, Germany.
  • Dettmer K; Institute of Human Genetics, Ulm University and Ulm University Medical Center, Ulm, Germany.
  • Schoeler A; Institute of Functional Genomics, University of Regensburg, Regensburg, Germany.
  • Lenze D; Department of Neuropathology, Charité, Medical University of Berlin, corporate member of Free University Berlin, Humboldt-University Berlin, and Berlin Institute of Health, Berlin, Germany.
  • Oefner PJ; German Cancer Consortium (DKTK); Partner Site Berlin, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Beule D; Department of Experimental Hematopathology, Institute of Pathology, Charité Medical University, Berlin, Charitéplatz 1, 10117, Berlin, Germany.
  • Siebert R; Berlin School of Integrative Oncology, Charité - Medical University of Berlin, Berlin, Germany.
  • Capper D; Berlin Institute of Health, Charité Core Unit Bioinformatics, Berlin, Germany.
  • Dimitrova L; Institute of Human Genetics, Ulm University and Ulm University Medical Center, Ulm, Germany.
  • Hummel M; Berlin School of Integrative Oncology, Charité - Medical University of Berlin, Berlin, Germany.
BMC Cancer ; 20(1): 427, 2020 May 14.
Article en En | MEDLINE | ID: mdl-32408898
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Adenosina / Linfoma de Células B / Apoptosis / Resistencia a Antineoplásicos / Adenosilhomocisteinasa / Variaciones en el Número de Copia de ADN / Proteína Potenciadora del Homólogo Zeste 2 Límite: Humans Idioma: En Revista: BMC Cancer Asunto de la revista: NEOPLASIAS Año: 2020 Tipo del documento: Article País de afiliación: Alemania
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Adenosina / Linfoma de Células B / Apoptosis / Resistencia a Antineoplásicos / Adenosilhomocisteinasa / Variaciones en el Número de Copia de ADN / Proteína Potenciadora del Homólogo Zeste 2 Límite: Humans Idioma: En Revista: BMC Cancer Asunto de la revista: NEOPLASIAS Año: 2020 Tipo del documento: Article País de afiliación: Alemania