Clinical characteristics of subglottic cancer: emphasis on therapeutic management strategies for stage II subglottic cancer.
Acta Otolaryngol
; 140(9): 773-778, 2020 Sep.
Article
en En
| MEDLINE
| ID: mdl-32491952
ABSTRACT
Background:
Subglottic cancer (SGC) is extremely rare, as most laryngeal cancers are localized to the glottic region. Accordingly, the clinical characteristics of SGC have not been well characterized.Objectives:
In the current study, SGCs were clinically evaluated, and the outcomes of radiotherapy (RT) in patients with stage II SGC were assessed.Materials andMethods:
Medical data derived from 11 patients with SGC, who were treated at our hospital between 1995 and 2019, were retrospectively reviewed.Results:
In our department SGC accounted for 3.9% of the 280 laryngeal cancer patients treated during the study period. At the time of SGC diagnosis, 9 (81.8%) had stage II cancer, 1 had stage III cancer, and 1 had stage IV cancer. Stage II SGC patients treated with concurrent chemoradiotherapy (CCRT) showed a significantly higher local control rate (p = .026) and laryngeal dysfunction free rate (p = .026) than those treated with RT alone. Salvage surgery, performed in 4 patients whose disease was not locally controlled with CCRT/RT, was successful in 3 patients.Conclusion:
As a treatment strategy for stage II SGC, CCRT is an acceptable initial treatment for laryngeal function and preservation while salvage surgery is effective for recurrence after CCRT/RT treatment.Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Carcinoma de Células Escamosas
/
Neoplasias Laríngeas
/
Quimioradioterapia
Tipo de estudio:
Observational_studies
Límite:
Aged
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Aged80
/
Humans
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Male
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Middle aged
Idioma:
En
Revista:
Acta Otolaryngol
Año:
2020
Tipo del documento:
Article
País de afiliación:
Japón