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Structure guided development of potent piperazine-derived hydroxamic acid inhibitors targeting falcilysin.
Kahlon, Gulbag; Lira, Rogelio; Masvlov, Nikolay; Pompa, Emmett; Brar, Nimrat; Eagon, Scott; Anderson, Marc O; Andaya, Armann; Chance, Jeff P; Fejzic, Hannah; Keniston, Aaron; Huynh, Ngoc; Celis, Nohemy; Vidal, Brian; Trieu, Nicholas; Rodriguez, Paulina; Mallari, Jeremy P.
Afiliación
  • Kahlon G; Department of Chemistry and Biochemistry, California State University, San Bernardino, USA.
  • Lira R; Department of Chemistry and Biochemistry, California State University, San Bernardino, USA.
  • Masvlov N; Department of Chemistry and Biochemistry, California State University, San Bernardino, USA.
  • Pompa E; Department of Chemistry and Biochemistry, California State University, San Bernardino, USA.
  • Brar N; Department of Chemistry and Biochemistry, California State University, San Bernardino, USA.
  • Eagon S; Department of Chemistry and Biochemistry, California Polytechnic State University, San Luis Obispo, USA.
  • Anderson MO; Department of Chemistry and Biochemistry, San Francisco State University, San Francisco, USA.
  • Andaya A; Campus Mass Spectrometry Facilities, University of California, Davis, USA.
  • Chance JP; Department of Chemistry and Biochemistry, California State University, San Bernardino, USA.
  • Fejzic H; Department of Chemistry and Biochemistry, California State University, San Bernardino, USA.
  • Keniston A; Department of Chemistry and Biochemistry, California State University, San Bernardino, USA.
  • Huynh N; Department of Chemistry and Biochemistry, California State University, San Bernardino, USA.
  • Celis N; Department of Chemistry and Biochemistry, California State University, San Bernardino, USA.
  • Vidal B; Department of Chemistry and Biochemistry, California State University, San Bernardino, USA.
  • Trieu N; Department of Chemistry and Biochemistry, California State University, San Bernardino, USA.
  • Rodriguez P; Department of Chemistry and Biochemistry, California State University, San Bernardino, USA.
  • Mallari JP; Department of Chemistry and Biochemistry, California State University, San Bernardino, USA. Electronic address: jeremy.mallari@csusb.edu.
Bioorg Med Chem Lett ; 32: 127683, 2021 01 15.
Article en En | MEDLINE | ID: mdl-33227414
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Metaloendopeptidasas / Proteínas Protozoarias / Piperazina / Ácidos Hidroxámicos / Antimaláricos Tipo de estudio: Prognostic_studies Idioma: En Revista: Bioorg Med Chem Lett Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Metaloendopeptidasas / Proteínas Protozoarias / Piperazina / Ácidos Hidroxámicos / Antimaláricos Tipo de estudio: Prognostic_studies Idioma: En Revista: Bioorg Med Chem Lett Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos