Safety and bioactive potential of nanoparticles containing Cantaloupe melon (<i>Cucumis melo</i> L.) carotenoids in an experimental model of chronic inflammation.

Medeiros, Isaiane; de Oliveira, Grazielle Louise Ribeiro; de Queiroz, Jaluza Luana Carvalho; de Carvalho Gomes, Camila; de Carvalho, Fabiana Maria Coimbra; de Souza Lima, Maíra Conceição Jerônimo; Serquiz, Alexandre Coelho; de Andrade Santos, Pedro Paulo; da Silva Camillo, Christina; Maciel, Bruna Leal Lima; de Araújo Morais, Ana Heloneida; Passos, Thaís Souza

Safety and bioactive potential of nanoparticles containing Cantaloupe melon (Cucumis melo L.) carotenoids in an experimental model of chronic inflammation.

Medeiros, Isaiane; de Oliveira, Grazielle Louise Ribeiro; de Queiroz, Jaluza Luana Carvalho; de Carvalho Gomes, Camila; de Carvalho, Fabiana Maria Coimbra; de Souza Lima, Maíra Conceição Jerônimo; Serquiz, Alexandre Coelho; de Andrade Santos, Pedro Paulo; da Silva Camillo, Christina; Maciel, Bruna Leal Lima; de Araújo Morais, Ana Heloneida; Passos, Thaís Souza.

Afiliación

Medeiros I; Postgraduate Program in Nutrition, Health Sciences Center, Federal University of Rio Grande do Norte, Natal, Brazil.
de Oliveira GLR; Postgraduate Program in Nutrition, Health Sciences Center, Federal University of Rio Grande do Norte, Natal, Brazil.
de Queiroz JLC; Postgraduate Program in Biochemistry, Center for Biosciences, Federal University of Rio Grande do Norte, Natal, Brazil.
de Carvalho Gomes C; Postgraduate Program in Biochemistry, Center for Biosciences, Federal University of Rio Grande do Norte, Natal, Brazil.
de Carvalho FMC; Postgraduate Program in Biochemistry, Center for Biosciences, Federal University of Rio Grande do Norte, Natal, Brazil.
de Souza Lima MCJ; Nutrition Course, Potiguar University, Natal, Brazil.
Serquiz AC; Veterinary Medicine Course, Potiguar University, Natal, Brazil.
de Andrade Santos PP; Nutrition Course, University Center of Rio Grande do Norte, Natal, Brazil.
da Silva Camillo C; Postgraduate Program in Structural and Functional Biology, Center for Biosciences, Federal University of Rio Grande do Norte, Natal, Brazil.
Maciel BLL; Department of Morphology, Center for Biosciences, Federal University of Rio Grande do Norte, Natal, Brazil.
de Araújo Morais AH; Postgraduate Program in Structural and Functional Biology, Center for Biosciences, Federal University of Rio Grande do Norte, Natal, Brazil.
Passos TS; Department of Morphology, Center for Biosciences, Federal University of Rio Grande do Norte, Natal, Brazil.

Biotechnol Rep (Amst) ; 28: e00567, 2020 Dec.

Article en En | MEDLINE | ID: mdl-33304841

Palabras clave

ALP, alkaline phosphatase; ALT, alanine aminotransferase; AST, aspartate transferase; BSD, Bowman's space dilation; CE, crude carotenoid extract; CEUA, Ethics Committee on the Use of Animals; Curcubitaceae; EI, efficiency of incorporation; EPG, crude carotenoid extract from Cantaloupe melon nanoencapsulated in porcine gelatin; FTIR, Fourier Transform Infrared Spectroscopy; GGT, gamma-glutamyl transferase; HGLI, high glycemic index and high glycemic load; IIF, inflammatory infiltrate foci; Nanotechnology; OECD, Organization for Economic Co-operation and Development; Obesity; PHT, presence of hypertrophic tubules; PIGI, percentage of intestinal gland integrity; PUV, percentage of ulcerated villi; PVA, percentage of villous absence; PVI, percentage of villus integrity; PVN, percentage of villous necrosis; SEM, Scanning Electron Microscope; THC, tubular hyaline cylinders; Toxicity; ß-carotene

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Biotechnol Rep (Amst) Año: 2020 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Países Bajos

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