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Metabolic compensation activates pro-survival mTORC1 signaling upon 3-phosphoglycerate dehydrogenase inhibition in osteosarcoma.
Rathore, Richa; Caldwell, Katharine E; Schutt, Charles; Brashears, Caitlyn B; Prudner, Bethany C; Ehrhardt, William R; Leung, Cheuk Hong; Lin, Heather; Daw, Najat C; Beird, Hannah C; Giles, Abigail; Wang, Wei-Lien; Lazar, Alexander J; Chrisinger, John S A; Livingston, J Andrew; Van Tine, Brian A.
Afiliación
  • Rathore R; Department of Medicine, Division of Medical Oncology, Washington University in St. Louis, St. Louis, MO 63110, USA.
  • Caldwell KE; Department of Surgery, Division of Hepatobiliary Surgery, Washington University in St. Louis, St. Louis, MO 63110, USA.
  • Schutt C; Department of Medicine, Division of Medical Oncology, Washington University in St. Louis, St. Louis, MO 63110, USA.
  • Brashears CB; Department of Medicine, Division of Medical Oncology, Washington University in St. Louis, St. Louis, MO 63110, USA.
  • Prudner BC; Department of Medicine, Division of Medical Oncology, Washington University in St. Louis, St. Louis, MO 63110, USA.
  • Ehrhardt WR; Department of Medicine, Division of Medical Oncology, Washington University in St. Louis, St. Louis, MO 63110, USA.
  • Leung CH; Department of Biostatistics, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Lin H; Department of Biostatistics, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Daw NC; Division of Pediatrics, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Beird HC; Department of Genomic Medicine, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Giles A; Department of Medicine, Division of Medical Oncology, Washington University in St. Louis, St. Louis, MO 63110, USA.
  • Wang WL; Department of Pathology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Lazar AJ; Department of Genomic Medicine, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Department of Pathology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Chrisinger JSA; Department of Pathology and Immunology, Washington University in St. Louis, St. Louis, MO 63110, USA.
  • Livingston JA; Department of Pathology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Department of Sarcoma Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Van Tine BA; Department of Medicine, Division of Medical Oncology, Washington University in St. Louis, St. Louis, MO 63110, USA; Siteman Cancer Center, St. Louis, MO 63110, USA. Electronic address: bvantine@wustl.edu.
Cell Rep ; 34(4): 108678, 2021 01 26.
Article en En | MEDLINE | ID: mdl-33503424
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Óseas / Osteosarcoma / Fosfoglicerato-Deshidrogenasa / Diana Mecanicista del Complejo 1 de la Rapamicina Límite: Humans Idioma: En Revista: Cell Rep Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Óseas / Osteosarcoma / Fosfoglicerato-Deshidrogenasa / Diana Mecanicista del Complejo 1 de la Rapamicina Límite: Humans Idioma: En Revista: Cell Rep Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos