TSP1 is the essential domain of SEMA5A involved in pannus formation in rheumatoid arthritis.

Xiao, Chipeng; Lv, Chen; Sun, Siyuan; Zhao, Heping; Ling, Hanzhi; Li, Man; Qin, Yang; Zhang, Jinhao; Wang, Jianguang; Yang, Xinyu

Xiao, Chipeng; Lv, Chen; Sun, Siyuan; Zhao, Heping; Ling, Hanzhi; Li, Man; Qin, Yang; Zhang, Jinhao; Wang, Jianguang; Yang, Xinyu.

Afiliación

Xiao C; Department of Biochemistry, School of Basic Medical Sciences, Wenzhou Medical University.
Lv C; Department of Orthopedics, Wenzhou Medical University First Affiliated Hospital.
Sun S; Department of Biochemistry, School of Basic Medical Sciences, Wenzhou Medical University.
Zhao H; Department of Biochemistry, School of Basic Medical Sciences, Wenzhou Medical University.
Ling H; Department of Biochemistry, School of Basic Medical Sciences, Wenzhou Medical University.
Li M; Department of Biochemistry, School of Basic Medical Sciences, Wenzhou Medical University.
Qin Y; Department of Biochemistry, School of Basic Medical Sciences, Wenzhou Medical University.
Zhang J; Department of Biochemistry, School of Basic Medical Sciences, Wenzhou Medical University.
Wang J; Department of Biochemistry, School of Basic Medical Sciences, Wenzhou Medical University.
Yang X; Department of Medicinal Chemistry, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, China.

Rheumatology (Oxford) ; 60(12): 5833-5842, 2021 12 01.

Article en En | MEDLINE | ID: mdl-33616619

Asunto(s)

Artritis Experimental/genética; Artritis Reumatoide/genética; Factores de Transcripción Básicos con Cremalleras de Leucinas y Motivos Hélice-Asa-Hélice/genética; Regulación de la Expresión Génica; ARN/genética; Semaforinas/genética; Adulto; Anciano; Anciano de 80 o más Años; Animales; Artritis Experimental/metabolismo; Artritis Experimental/patología; Artritis Reumatoide/metabolismo; Artritis Reumatoide/patología; Factores de Transcripción Básicos con Cremalleras de Leucinas y Motivos Hélice-Asa-Hélice/biosíntesis; Western Blotting; Movimiento Celular; Proliferación Celular; Femenino; Fibroblastos/metabolismo; Fibroblastos/patología; Estudios de Seguimiento; Secuencias Hélice-Asa-Hélice; Humanos; Masculino; Ratones; Ratones Endogámicos DBA; Persona de Mediana Edad; Estudios Retrospectivos; Semaforinas/biosíntesis; Sinoviocitos/metabolismo; Sinoviocitos/patología; Trombospondina 1

Palabras clave

RA; SEMA5A; TSP1 domain; angiogenesis

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Artritis Experimental / Artritis Reumatoide / ARN / Regulación de la Expresión Génica / Semaforinas / Factores de Transcripción Básicos con Cremalleras de Leucinas y Motivos Hélice-Asa-Hélice Tipo de estudio: Observational_studies / Prognostic_studies Límite: Adult / Aged / Aged80 / Animals / Female / Humans / Male / Middle aged Idioma: En Revista: Rheumatology (Oxford) Asunto de la revista: REUMATOLOGIA Año: 2021 Tipo del documento: Article Pais de publicación: Reino Unido

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