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Shorter androgen receptor polyQ alleles protect against life-threatening COVID-19 disease in European males.
Baldassarri, Margherita; Picchiotti, Nicola; Fava, Francesca; Fallerini, Chiara; Benetti, Elisa; Daga, Sergio; Valentino, Floriana; Doddato, Gabriella; Furini, Simone; Giliberti, Annarita; Tita, Rossella; Amitrano, Sara; Bruttini, Mirella; Croci, Susanna; Meloni, Ilaria; Pinto, Anna Maria; Iuso, Nicola; Gabbi, Chiara; Sciarra, Francesca; Venneri, Mary Anna; Gori, Marco; Sanarico, Maurizio; Crawley, Francis P; Pagotto, Uberto; Fanelli, Flaminia; Mezzullo, Marco; Dominguez-Garrido, Elena; Planas-Serra, Laura; Schlüter, Agatha; Colobran, Roger; Soler-Palacin, Pere; Lapunzina, Pablo; Tenorio, Jair; Pujol, Aurora; Castagna, Maria Grazia; Marcelli, Marco; Isidori, Andrea M; Renieri, Alessandra; Frullanti, Elisa; Mari, Francesca.
Afiliación
  • Baldassarri M; Medical Genetics, University of Siena, Italy; Med Biotech Hub and Competence Center, Department of Medical Biotechnologies, University of Siena, Italy.
  • Picchiotti N; University of Siena, DIISM-SAILAB, Siena, Italy; Department of Mathematics, University of Pavia, Pavia, Italy.
  • Fava F; Medical Genetics, University of Siena, Italy; Med Biotech Hub and Competence Center, Department of Medical Biotechnologies, University of Siena, Italy; Genetica Medica, Azienda Ospedaliero-Universitaria Senese, Italy.
  • Fallerini C; Medical Genetics, University of Siena, Italy; Med Biotech Hub and Competence Center, Department of Medical Biotechnologies, University of Siena, Italy.
  • Benetti E; Med Biotech Hub and Competence Center, Department of Medical Biotechnologies, University of Siena, Italy.
  • Daga S; Medical Genetics, University of Siena, Italy; Med Biotech Hub and Competence Center, Department of Medical Biotechnologies, University of Siena, Italy.
  • Valentino F; Medical Genetics, University of Siena, Italy; Med Biotech Hub and Competence Center, Department of Medical Biotechnologies, University of Siena, Italy.
  • Doddato G; Medical Genetics, University of Siena, Italy; Med Biotech Hub and Competence Center, Department of Medical Biotechnologies, University of Siena, Italy.
  • Furini S; Med Biotech Hub and Competence Center, Department of Medical Biotechnologies, University of Siena, Italy.
  • Giliberti A; Medical Genetics, University of Siena, Italy; Med Biotech Hub and Competence Center, Department of Medical Biotechnologies, University of Siena, Italy.
  • Tita R; Genetica Medica, Azienda Ospedaliero-Universitaria Senese, Italy.
  • Amitrano S; Genetica Medica, Azienda Ospedaliero-Universitaria Senese, Italy.
  • Bruttini M; Medical Genetics, University of Siena, Italy; Med Biotech Hub and Competence Center, Department of Medical Biotechnologies, University of Siena, Italy; Genetica Medica, Azienda Ospedaliero-Universitaria Senese, Italy.
  • Croci S; Medical Genetics, University of Siena, Italy; Med Biotech Hub and Competence Center, Department of Medical Biotechnologies, University of Siena, Italy.
  • Meloni I; Medical Genetics, University of Siena, Italy; Med Biotech Hub and Competence Center, Department of Medical Biotechnologies, University of Siena, Italy.
  • Pinto AM; Genetica Medica, Azienda Ospedaliero-Universitaria Senese, Italy.
  • Iuso N; Medical Genetics, University of Siena, Italy; Med Biotech Hub and Competence Center, Department of Medical Biotechnologies, University of Siena, Italy.
  • Gabbi C; Independent Medical Scientist, Milan, Italy.
  • Sciarra F; Department of Experimental Medicine, Sapienza University of Rome, Rome, Italy.
  • Venneri MA; Department of Experimental Medicine, Sapienza University of Rome, Rome, Italy.
  • Gori M; University of Siena, DIISM-SAILAB, Siena, Italy; Université Côte d'Azur, Inria, CNRS, I3S, Maasai.
  • Sanarico M; Independent Data Scientist, Milan, Italy.
  • Crawley FP; Good Clinical Practice Alliance-Europe (GCPA) and Strategic Initiative for Developing Capacity in Ethical Review-Europe (SIDCER), Leuven, Belgium.
  • Pagotto U; Unit of Endocrinology and Prevention and Care of Diabetes, Center for Applied, Biomedical Research, Department of Medical and Surgical Sciences, University of Bologna, S. Orsola-Malpighi Hospital, Bologna, Italy.
  • Fanelli F; Unit of Endocrinology and Prevention and Care of Diabetes, Center for Applied, Biomedical Research, Department of Medical and Surgical Sciences, University of Bologna, S. Orsola-Malpighi Hospital, Bologna, Italy.
  • Mezzullo M; Unit of Endocrinology and Prevention and Care of Diabetes, Center for Applied, Biomedical Research, Department of Medical and Surgical Sciences, University of Bologna, S. Orsola-Malpighi Hospital, Bologna, Italy.
  • Dominguez-Garrido E; Molecular Diagnostic Unit, Fundación Rioja Salud, Logroño, La Rioja, Spain.
  • Planas-Serra L; Neurometabolic Diseases Laboratory, Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Spain; CIBERER, Centro de Investigación Biomédica en Red de Enfermedades Raras, ISCIII, Melchor Fernández Almagro, 3, 28029 Madrid, Spain; Spanish Covid HGE.
  • Schlüter A; Neurometabolic Diseases Laboratory, Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Spain; CIBERER, Centro de Investigación Biomédica en Red de Enfermedades Raras, ISCIII, Melchor Fernández Almagro, 3, 28029 Madrid, Spain; Spanish Covid HGE.
  • Colobran R; Immunology Division, Genetics Department, Hospital Universitari Vall d'Hebron, Vall d'Hebron Research Institute, Vall d'Hebron Barcelona Hospital Campus, Universitat Autònoma de Barcelona (UAB), Barcelona, Catalonia, Spain, EU.
  • Soler-Palacin P; Pediatric Infectious Diseases and Immunodeficiencies Unit, Hospital Universitari Vall d'Hebron, Vall d'Hebron Research Institute, Barcelona, Catalonia, Spain.
  • Lapunzina P; CIBERER, Centro de Investigación Biomédica en Red de Enfermedades Raras, ISCIII, Melchor Fernández Almagro, 3, 28029 Madrid, Spain; Institute of Medical and Molecular Genetics (INGEMM)-IdiPAZ, Hospital Universitario La Paz-UAM Paseo de La Castellana, 261, 28046 Madrid, Spain.
  • Tenorio J; CIBERER, Centro de Investigación Biomédica en Red de Enfermedades Raras, ISCIII, Melchor Fernández Almagro, 3, 28029 Madrid, Spain; Institute of Medical and Molecular Genetics (INGEMM)-IdiPAZ, Hospital Universitario La Paz-UAM Paseo de La Castellana, 261, 28046 Madrid, Spain.
  • Pujol A; Neurometabolic Diseases Laboratory, Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Spain; CIBERER, Centro de Investigación Biomédica en Red de Enfermedades Raras, ISCIII, Melchor Fernández Almagro, 3, 28029 Madrid, Spain; Catalan Institution for Research and Advanced Studies (ICREA),
  • Castagna MG; Department of Medical, Surgical and Neurological Sciences, University of Siena, Italy.
  • Marcelli M; Department of Medicine, Baylor College of Medicine, Houston TX, USA.
  • Isidori AM; Department of Experimental Medicine, Sapienza University of Rome, Rome, Italy.
  • Renieri A; Medical Genetics, University of Siena, Italy; Med Biotech Hub and Competence Center, Department of Medical Biotechnologies, University of Siena, Italy; Genetica Medica, Azienda Ospedaliero-Universitaria Senese, Italy. Electronic address: alessandra.renieri@unisi.it.
  • Frullanti E; Medical Genetics, University of Siena, Italy; Med Biotech Hub and Competence Center, Department of Medical Biotechnologies, University of Siena, Italy.
  • Mari F; Medical Genetics, University of Siena, Italy; Med Biotech Hub and Competence Center, Department of Medical Biotechnologies, University of Siena, Italy; Genetica Medica, Azienda Ospedaliero-Universitaria Senese, Italy.
EBioMedicine ; 65: 103246, 2021 Mar.
Article en En | MEDLINE | ID: mdl-33647767
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Péptidos / Receptores Androgénicos / COVID-19 Tipo de estudio: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Aged / Female / Humans / Male / Middle aged País/Región como asunto: Europa Idioma: En Revista: EBioMedicine Año: 2021 Tipo del documento: Article País de afiliación: Italia
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Péptidos / Receptores Androgénicos / COVID-19 Tipo de estudio: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Aged / Female / Humans / Male / Middle aged País/Región como asunto: Europa Idioma: En Revista: EBioMedicine Año: 2021 Tipo del documento: Article País de afiliación: Italia