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JNK signaling prevents biliary cyst formation through a CASPASE-8-dependent function of RIPK1 during aging.
Müller, Katrin; Honcharova-Biletska, Hanna; Koppe, Christiane; Egger, Michèle; Chan, Lap Kwan; Schneider, Anne T; Küsgens, Lena; Böhm, Friederike; Boege, Yannick; Healy, Marc E; Schmitt, Johannes; Comtesse, Sarah; Castoldi, Mirco; Preisinger, Christian; Szydlowska, Marta; Focaccia, Enrico; Gaisa, Nadine T; Loosen, Sven H; Jörs, Simone; Tacke, Frank; Roderburg, Christoph; Keitel, Verena; Bode, Johannes G; Boor, Peter; Davis, Roger J; Longerich, Thomas; Geisler, Fabian; Heikenwalder, Mathias; Weber, Achim; Vucur, Mihael; Luedde, Tom.
Afiliación
  • Müller K; Division of Biliary and Gastrointestinal Oncology, University Hospital Rheinisch-Westfälische Technische Hochschule (RWTH) Aachen, 52074 Aachen, Germany.
  • Honcharova-Biletska H; Department of Pathology and Molecular Pathology, University of Zurich and University Hospital Zurich, 8091 Zurich, Switzerland.
  • Koppe C; Division of Biliary and Gastrointestinal Oncology, University Hospital Rheinisch-Westfälische Technische Hochschule (RWTH) Aachen, 52074 Aachen, Germany.
  • Egger M; Department of Pathology and Molecular Pathology, University of Zurich and University Hospital Zurich, 8091 Zurich, Switzerland.
  • Chan LK; Department of Pathology and Molecular Pathology, University of Zurich and University Hospital Zurich, 8091 Zurich, Switzerland.
  • Schneider AT; Division of Biliary and Gastrointestinal Oncology, University Hospital Rheinisch-Westfälische Technische Hochschule (RWTH) Aachen, 52074 Aachen, Germany.
  • Küsgens L; Division of Biliary and Gastrointestinal Oncology, University Hospital Rheinisch-Westfälische Technische Hochschule (RWTH) Aachen, 52074 Aachen, Germany.
  • Böhm F; Department of Pathology and Molecular Pathology, University of Zurich and University Hospital Zurich, 8091 Zurich, Switzerland.
  • Boege Y; Department of Pathology and Molecular Pathology, University of Zurich and University Hospital Zurich, 8091 Zurich, Switzerland.
  • Healy ME; Department of Pathology and Molecular Pathology, University of Zurich and University Hospital Zurich, 8091 Zurich, Switzerland.
  • Schmitt J; Department of Pathology and Molecular Pathology, University of Zurich and University Hospital Zurich, 8091 Zurich, Switzerland.
  • Comtesse S; Department of Pathology and Molecular Pathology, University of Zurich and University Hospital Zurich, 8091 Zurich, Switzerland.
  • Castoldi M; Division of Biliary and Gastrointestinal Oncology, University Hospital Rheinisch-Westfälische Technische Hochschule (RWTH) Aachen, 52074 Aachen, Germany.
  • Preisinger C; Department of Gastroenterology, Hepatology and Infectious Diseases, University Hospital Duesseldorf, Medical Faculty, Heinrich Heine University, 40225 Duesseldorf, Germany.
  • Szydlowska M; Proteomics Core Facility, Interdisciplinary Center for Clinical Research, University Hospital RWTH Aachen, 52074 Aachen, Germany.
  • Focaccia E; Division of Chronic Inflammation and Cancer, German Cancer Research Center (Deutsches Krebsforschungszentrum), 69120 Heidelberg, Germany.
  • Gaisa NT; Division of Chronic Inflammation and Cancer, German Cancer Research Center (Deutsches Krebsforschungszentrum), 69120 Heidelberg, Germany.
  • Loosen SH; Institute of Pathology, University Hospital RWTH Aachen, 52074 Aachen, Germany.
  • Jörs S; Department of Gastroenterology, Hepatology and Infectious Diseases, University Hospital Duesseldorf, Medical Faculty, Heinrich Heine University, 40225 Duesseldorf, Germany.
  • Tacke F; Internal Medicine II, Klinikum rechts der Isar, Technical University Munich, 81675 Munich, Germany.
  • Roderburg C; Department of Hepatology and Gastroenterology, Charité University Medical Center Berlin, 10117 Berlin, Germany.
  • Keitel V; Department of Hepatology and Gastroenterology, Charité University Medical Center Berlin, 10117 Berlin, Germany.
  • Bode JG; Department of Gastroenterology, Hepatology and Infectious Diseases, University Hospital Duesseldorf, Medical Faculty, Heinrich Heine University, 40225 Duesseldorf, Germany.
  • Boor P; Department of Gastroenterology, Hepatology and Infectious Diseases, University Hospital Duesseldorf, Medical Faculty, Heinrich Heine University, 40225 Duesseldorf, Germany.
  • Davis RJ; Institute of Pathology, University Hospital RWTH Aachen, 52074 Aachen, Germany.
  • Longerich T; Department of Nephrology and Immunology, University Hospital RWTH Aachen, 52074 Aachen, Germany.
  • Geisler F; Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA 01605.
  • Heikenwalder M; Institute of Pathology, University Hospital Heidelberg, 69120 Heidelberg, Germany.
  • Weber A; Internal Medicine II, Klinikum rechts der Isar, Technical University Munich, 81675 Munich, Germany.
  • Vucur M; Division of Chronic Inflammation and Cancer, German Cancer Research Center (Deutsches Krebsforschungszentrum), 69120 Heidelberg, Germany.
  • Luedde T; Department of Pathology and Molecular Pathology, University of Zurich and University Hospital Zurich, 8091 Zurich, Switzerland; achim.weber@usz.ch luedde@hhu.de.
Proc Natl Acad Sci U S A ; 118(12)2021 03 23.
Article en En | MEDLINE | ID: mdl-33798093
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedades de los Conductos Biliares / Envejecimiento / Sistema de Señalización de MAP Quinasas / Quistes / Caspasa 8 / Proteína Serina-Treonina Quinasas de Interacción con Receptores Tipo de estudio: Etiology_studies Límite: Animals Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2021 Tipo del documento: Article País de afiliación: Alemania
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedades de los Conductos Biliares / Envejecimiento / Sistema de Señalización de MAP Quinasas / Quistes / Caspasa 8 / Proteína Serina-Treonina Quinasas de Interacción con Receptores Tipo de estudio: Etiology_studies Límite: Animals Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2021 Tipo del documento: Article País de afiliación: Alemania