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RAC1B modulates intestinal tumourigenesis via modulation of WNT and EGFR signalling pathways.
Gudiño, Victoria; Pohl, Sebastian Öther-Gee; Billard, Caroline V; Cammareri, Patrizia; Bolado, Alfonso; Aitken, Stuart; Stevenson, David; Hall, Adam E; Agostino, Mark; Cassidy, John; Nixon, Colin; von Kriegsheim, Alex; Freile, Paz; Popplewell, Linda; Dickson, George; Murphy, Laura; Wheeler, Ann; Dunlop, Malcolm; Din, Farhat; Strathdee, Douglas; Sansom, Owen J; Myant, Kevin B.
Afiliación
  • Gudiño V; Cancer Research UK Edinburgh Centre, MRC Institute of Genetics & Molecular Medicine, The University of Edinburgh, Western General Hospital, Edinburgh, EH4 2XU, UK.
  • Pohl SÖ; Inflammatory Bowel Disease Unit, Department of Gastroenterology, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) - CIBEREHD, Barcelona, Spain.
  • Billard CV; Cancer Research UK Edinburgh Centre, MRC Institute of Genetics & Molecular Medicine, The University of Edinburgh, Western General Hospital, Edinburgh, EH4 2XU, UK.
  • Cammareri P; Cancer Research UK Edinburgh Centre, MRC Institute of Genetics & Molecular Medicine, The University of Edinburgh, Western General Hospital, Edinburgh, EH4 2XU, UK.
  • Bolado A; Cancer Research UK Edinburgh Centre, MRC Institute of Genetics & Molecular Medicine, The University of Edinburgh, Western General Hospital, Edinburgh, EH4 2XU, UK.
  • Aitken S; Cancer Research UK Edinburgh Centre, MRC Institute of Genetics & Molecular Medicine, The University of Edinburgh, Western General Hospital, Edinburgh, EH4 2XU, UK.
  • Stevenson D; MRC Human Genetics Unit, MRC Institute of Genetics & Molecular Medicine, The University of Edinburgh, Western General Hospital, Edinburgh, EH4 2XU, UK.
  • Hall AE; Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, EH4 2XU, UK.
  • Agostino M; Cancer Research UK Beatson Institute, Garscube Estate, Bearsden, Glasgow, G61 1BD, UK.
  • Cassidy J; Cancer Research UK Edinburgh Centre, MRC Institute of Genetics & Molecular Medicine, The University of Edinburgh, Western General Hospital, Edinburgh, EH4 2XU, UK.
  • Nixon C; School of Pharmacy and Biomedical Sciences, Curtin Health and Innovation Research Institute, Curtin University, Perth, WA, 6845, Australia.
  • von Kriegsheim A; Curtin Institute for Computation, Curtin University, Perth, WA, 6845, Australia.
  • Freile P; Cancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Cambridge, CB2 0RE, UK.
  • Popplewell L; Cancer Research UK Beatson Institute, Garscube Estate, Bearsden, Glasgow, G61 1BD, UK.
  • Dickson G; Cancer Research UK Edinburgh Centre, MRC Institute of Genetics & Molecular Medicine, The University of Edinburgh, Western General Hospital, Edinburgh, EH4 2XU, UK.
  • Murphy L; Cancer Research UK Edinburgh Centre, MRC Institute of Genetics & Molecular Medicine, The University of Edinburgh, Western General Hospital, Edinburgh, EH4 2XU, UK.
  • Wheeler A; MRC Human Genetics Unit, MRC Institute of Genetics & Molecular Medicine, The University of Edinburgh, Western General Hospital, Edinburgh, EH4 2XU, UK.
  • Dunlop M; Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, EH4 2XU, UK.
  • Din F; School of Biological Sciences, Royal Holloway - University of London, Egham, Surrey, TW20 0EX, UK.
  • Strathdee D; School of Biological Sciences, Royal Holloway - University of London, Egham, Surrey, TW20 0EX, UK.
  • Sansom OJ; Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, EH4 2XU, UK.
  • Myant KB; Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, EH4 2XU, UK.
Nat Commun ; 12(1): 2335, 2021 04 20.
Article en En | MEDLINE | ID: mdl-33879799
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Colorrectales / Proteína de Unión al GTP rac1 Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans / Male Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2021 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Colorrectales / Proteína de Unión al GTP rac1 Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans / Male Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2021 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Reino Unido