Development, Testing, Parameterisation and Calibration of a Human PBPK Model for the Plasticiser, Di-(2-propylheptyl) Phthalate (DPHP) Using in Silico, <i>in vitro</i> and Human Biomonitoring Data.

McNally, Kevin; Sams, Craig; Hogg, Alex; Lumen, Annie; Loizou, George

Development, Testing, Parameterisation and Calibration of a Human PBPK Model for the Plasticiser, Di-(2-propylheptyl) Phthalate (DPHP) Using in Silico, in vitro and Human Biomonitoring Data.

McNally, Kevin; Sams, Craig; Hogg, Alex; Lumen, Annie; Loizou, George.

Afiliación

McNally K; Health and Safety Executive, Buxton, United Kingdom.
Sams C; Health and Safety Executive, Buxton, United Kingdom.
Hogg A; Health and Safety Executive, Buxton, United Kingdom.
Lumen A; National Center for Toxicological Research, US Food and Drug Administration, Jefferson, AR, United States.
Loizou G; Health and Safety Executive, Buxton, United Kingdom.

Front Pharmacol ; 12: 692442, 2021.

Article en En | MEDLINE | ID: mdl-34539393

Palabras clave

DPHP; PBPK; bayesian; biomonitoring; in silico; in vitro; markov chain Monte Carlo; plasticiser

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Prognostic_studies / Qualitative_research Idioma: En Revista: Front Pharmacol Año: 2021 Tipo del documento: Article País de afiliación: Reino Unido

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