Genome-Wide Epigenomic Analyses in Patients With Nociceptive and Neuropathic Chronic Pain Subtypes Reveals Alterations in Methylation of Genes Involved in the Neuro-Musculoskeletal System.

Stenz, Ludwig; Carré, Joane Le; Luthi, François; Vuistiner, Philippe; Burrus, Cyrille; Paoloni-Giacobino, Ariane; Léger, Bertrand

Stenz, Ludwig; Carré, Joane Le; Luthi, François; Vuistiner, Philippe; Burrus, Cyrille; Paoloni-Giacobino, Ariane; Léger, Bertrand.

Afiliación

Stenz L; Department of Genetic Medicine and Development, Geneva University, Medicine Faculty, Geneva, Switzerland.
Carré JL; Institute for Research in Rehabilitation, Clinique romande de réadaptation, Sion, Switzerland; Department of Medical Research, Clinique romande de réadaptation, Sion, Switzerland.
Luthi F; Institute for Research in Rehabilitation, Clinique romande de réadaptation, Sion, Switzerland; Department of Musculoskeletal Rehabilitation, Clinique romande de réadaptation, Sion, Switzerland; Department of Physical Medicine and Rehabilitation, Orthopaedic Hospital, Lausanne University Hospital, La
Vuistiner P; Institute for Research in Rehabilitation, Clinique romande de réadaptation, Sion, Switzerland; Department of Medical Research, Clinique romande de réadaptation, Sion, Switzerland.
Burrus C; Institute for Research in Rehabilitation, Clinique romande de réadaptation, Sion, Switzerland; Department of Musculoskeletal Rehabilitation, Clinique romande de réadaptation, Sion, Switzerland.
Paoloni-Giacobino A; Department of Genetic Medicine and Development, Geneva University, Medicine Faculty, Geneva, Switzerland.
Léger B; Institute for Research in Rehabilitation, Clinique romande de réadaptation, Sion, Switzerland; Department of Medical Research, Clinique romande de réadaptation, Sion, Switzerland. Electronic address: Bertrand.Leger@crr-suva.ch.

J Pain ; 23(2): 326-336, 2022 02.

Article en En | MEDLINE | ID: mdl-34547430

Asunto(s)

Dolor Crónico/genética; Epigenoma/genética; Estudios de Asociación Genética; Neuralgia/genética; Dolor Nociceptivo/genética; Adulto; Estudios de Cohortes; Metilación de ADN/genética; Femenino; Humanos; Masculino; Persona de Mediana Edad; Sistema Musculoesquelético/metabolismo; Sistema Nervioso/metabolismo

Palabras clave

DNA methylation; biomarkers; chronic pain; neuropathic pain; nociceptive pain

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Estudios de Asociación Genética / Dolor Crónico / Dolor Nociceptivo / Epigenoma / Neuralgia Tipo de estudio: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: J Pain Asunto de la revista: NEUROLOGIA / PSICOFISIOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: Suiza Pais de publicación: Estados Unidos

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