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Dolabellane Diterpenes and Elemane Alkaloids from the Soft Coral Clavularia inflata Collected in the South China Sea.
Han, Xiao; Luo, Xiangchao; Xue, Lei; van Ofwegen, Leen; Zhang, Wenjie; Liu, Kechun; Zhang, Yun; Tang, Xuli; Li, Pinglin; Li, Guoqiang.
Afiliación
  • Han X; Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, People's Republic of China.
  • Luo X; Laboratory of Marine Drugs and Biological Products, Pilot National Laboratory for Marine Science and Technology, Qingdao 266235, People's Republic of China.
  • Xue L; Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, People's Republic of China.
  • van Ofwegen L; Laboratory of Marine Drugs and Biological Products, Pilot National Laboratory for Marine Science and Technology, Qingdao 266235, People's Republic of China.
  • Zhang W; Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, People's Republic of China.
  • Liu K; Laboratory of Marine Drugs and Biological Products, Pilot National Laboratory for Marine Science and Technology, Qingdao 266235, People's Republic of China.
  • Zhang Y; National Natuurhistorisch Museum, 2300 RA Leiden, The Netherlands.
  • Tang X; Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, People's Republic of China.
  • Li P; Laboratory of Marine Drugs and Biological Products, Pilot National Laboratory for Marine Science and Technology, Qingdao 266235, People's Republic of China.
  • Li G; Biology Institute, Qilu University of Technology (Shandong Academy of Sciences), Jinan 28789, People's Republic of China.
J Nat Prod ; 85(1): 276-283, 2022 01 28.
Article en En | MEDLINE | ID: mdl-35018782
Five new dolabellane diterpenes, clavularinlides A-E (1-5), and four new racemic elemane alkaloids, clavulacylides A-D (7-10), together with one known compound (6), were isolated from the soft coral Clavularia inflata collected in the South China Sea. Their structures were elucidated by 1D and 2D NMR, HRESIMS, calculated ECD, and DP4+ probability analyses. Compounds 1-7 showed anti-inflammatory activity in the zebrafish assay.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Antozoos / Diterpenos / Sesquiterpenos Monocíclicos Límite: Animals País/Región como asunto: Asia Idioma: En Revista: J Nat Prod Año: 2022 Tipo del documento: Article Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Antozoos / Diterpenos / Sesquiterpenos Monocíclicos Límite: Animals País/Región como asunto: Asia Idioma: En Revista: J Nat Prod Año: 2022 Tipo del documento: Article Pais de publicación: Estados Unidos