Discovery of small-molecule positive allosteric modulators of Parkin E3 ligase.

Shlevkov, Evgeny; Murugan, Paramasivam; Montagna, Dan; Stefan, Eric; Hadzipasic, Adelajda; Harvey, James S; Kumar, P Rajesh; Entova, Sonya; Bansal, Nupur; Bickford, Shari; Wong, Lai-Yee; Hirst, Warren D; Weihofen, Andreas; Silvian, Laura F

Shlevkov, Evgeny; Murugan, Paramasivam; Montagna, Dan; Stefan, Eric; Hadzipasic, Adelajda; Harvey, James S; Kumar, P Rajesh; Entova, Sonya; Bansal, Nupur; Bickford, Shari; Wong, Lai-Yee; Hirst, Warren D; Weihofen, Andreas; Silvian, Laura F.

Afiliación

Shlevkov E; Neurodegenerative Disease Research Unit, Biogen, Cambridge, MA 02142, USA.
Murugan P; Biotherapeutics and Medicinal Sciences, Biogen, Cambridge, MA 02142, USA.
Montagna D; Neurodegenerative Disease Research Unit, Biogen, Cambridge, MA 02142, USA.
Stefan E; Biotherapeutics and Medicinal Sciences, Biogen, Cambridge, MA 02142, USA.
Hadzipasic A; Biotherapeutics and Medicinal Sciences, Biogen, Cambridge, MA 02142, USA.
Harvey JS; Biotherapeutics and Medicinal Sciences, Biogen, Cambridge, MA 02142, USA.
Kumar PR; Biotherapeutics and Medicinal Sciences, Biogen, Cambridge, MA 02142, USA.
Entova S; Biotherapeutics and Medicinal Sciences, Biogen, Cambridge, MA 02142, USA.
Bansal N; Biotherapeutics and Medicinal Sciences, Biogen, Cambridge, MA 02142, USA.
Bickford S; Biotherapeutics and Medicinal Sciences, Biogen, Cambridge, MA 02142, USA.
Wong LY; Biotherapeutics and Medicinal Sciences, Biogen, Cambridge, MA 02142, USA.
Hirst WD; Neurodegenerative Disease Research Unit, Biogen, Cambridge, MA 02142, USA.
Weihofen A; Neurodegenerative Disease Research Unit, Biogen, Cambridge, MA 02142, USA.
Silvian LF; Biotherapeutics and Medicinal Sciences, Biogen, Cambridge, MA 02142, USA.

iScience ; 25(1): 103650, 2022 Jan 21.

Article en En | MEDLINE | ID: mdl-35024585

Palabras clave

Biochemistry; Biochemistry Applications; Chemistry

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: IScience Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos

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