Flavonoids from Scutellaria barbata D. Don exert antitumor activity in colorectal cancer through inhibited autophagy and promoted apoptosis via ATF4/sestrin2 pathway.

Liu, Lianfang; Liu, Tianya; Tao, Weiwei; Liao, Naikai; Yan, Qiuying; Li, Liu; Tan, Jiani; Shen, Weixing; Cheng, Haibo; Sun, Dongdong

Liu, Lianfang; Liu, Tianya; Tao, Weiwei; Liao, Naikai; Yan, Qiuying; Li, Liu; Tan, Jiani; Shen, Weixing; Cheng, Haibo; Sun, Dongdong.

Afiliación

Liu L; Department of Medical Oncology, Zhangjiagang TCM Hospital Affiliated to Nanjing University of Chinese Medicine, Suzhou 215600, China; School of Integrated Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing 210023, China.
Liu T; School of Integrated Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing 210023, China.
Tao W; School of Integrated Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing 210023, China.
Liao N; Department of Urology, the First Affiliated Hospital of Guangxi Medical University, Naning 530021, China.
Yan Q; Collaborative Innovation Center of Jiangsu Province of Cancer Prevention and Treatment of Chinese Medicine, Nanjing 210023, China.
Li L; Collaborative Innovation Center of Jiangsu Province of Cancer Prevention and Treatment of Chinese Medicine, Nanjing 210023, China.
Tan J; Collaborative Innovation Center of Jiangsu Province of Cancer Prevention and Treatment of Chinese Medicine, Nanjing 210023, China.
Shen W; Collaborative Innovation Center of Jiangsu Province of Cancer Prevention and Treatment of Chinese Medicine, Nanjing 210023, China.
Cheng H; Collaborative Innovation Center of Jiangsu Province of Cancer Prevention and Treatment of Chinese Medicine, Nanjing 210023, China; Jiangsu Key Laboratory for TCM Formulae Research, Nanjing 210023, China. Electronic address: hbcheng_njucm@163.com.
Sun D; School of Integrated Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing 210023, China; Collaborative Innovation Center of Jiangsu Province of Cancer Prevention and Treatment of Chinese Medicine, Nanjing 210023, China; Jiangsu Key Laboratory for TCM Formulae Research, Nanji

Phytomedicine ; 99: 154007, 2022 May.

Article en En | MEDLINE | ID: mdl-35259610

Palabras clave

ATF4; Autophagy; Colorectal cancer; Scutellaria barbata D. Don; apoptosis; sestrin2

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Phytomedicine Asunto de la revista: TERAPIAS COMPLEMENTARES Año: 2022 Tipo del documento: Article País de afiliación: China

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