Your browser doesn't support javascript.
loading
Leveraging Structure-Based Drug Design to Identify Next-Generation MAT2A Inhibitors, Including Brain-Penetrant and Peripherally Efficacious Leads.
Li, Mingzong; Konteatis, Zenon; Nagaraja, Nelamangala; Chen, Yue; Zhou, Shubao; Ma, Guangning; Gross, Stefan; Marjon, Katya; Hyer, Marc L; Mandley, Everton; Lein, Max; Padyana, Anil K; Jin, Lei; Tong, Shuilong; Peters, Rachel; Murtie, Joshua; Travins, Jeremy; Medeiros, Matthew; Liu, Peng; Frank, Victoria; Judd, Evan T; Biller, Scott A; Marks, Kevin M; Sui, Zhihua; Reznik, Samuel K.
Afiliación
  • Li M; Agios Pharmaceuticals, Inc., 88 Sidney Street, Cambridge, Massachusetts 02139, United States.
  • Konteatis Z; Agios Pharmaceuticals, Inc., 88 Sidney Street, Cambridge, Massachusetts 02139, United States.
  • Nagaraja N; Agios Pharmaceuticals, Inc., 88 Sidney Street, Cambridge, Massachusetts 02139, United States.
  • Chen Y; Agios Pharmaceuticals, Inc., 88 Sidney Street, Cambridge, Massachusetts 02139, United States.
  • Zhou S; PharmaResources Co., Ltd., 509 Renqing Road, Pudong New Area, Shanghai 201201, China.
  • Ma G; PharmaResources Co., Ltd., 509 Renqing Road, Pudong New Area, Shanghai 201201, China.
  • Gross S; Agios Pharmaceuticals, Inc., 88 Sidney Street, Cambridge, Massachusetts 02139, United States.
  • Marjon K; Agios Pharmaceuticals, Inc., 88 Sidney Street, Cambridge, Massachusetts 02139, United States.
  • Hyer ML; Agios Pharmaceuticals, Inc., 88 Sidney Street, Cambridge, Massachusetts 02139, United States.
  • Mandley E; Agios Pharmaceuticals, Inc., 88 Sidney Street, Cambridge, Massachusetts 02139, United States.
  • Lein M; Agios Pharmaceuticals, Inc., 88 Sidney Street, Cambridge, Massachusetts 02139, United States.
  • Padyana AK; Agios Pharmaceuticals, Inc., 88 Sidney Street, Cambridge, Massachusetts 02139, United States.
  • Jin L; Agios Pharmaceuticals, Inc., 88 Sidney Street, Cambridge, Massachusetts 02139, United States.
  • Tong S; Viva Biotech, Ltd., 334 Aidisheng Road, Zhangjiang High-Tech Park, Shanghai 201203, China.
  • Peters R; Agios Pharmaceuticals, Inc., 88 Sidney Street, Cambridge, Massachusetts 02139, United States.
  • Murtie J; Agios Pharmaceuticals, Inc., 88 Sidney Street, Cambridge, Massachusetts 02139, United States.
  • Travins J; Agios Pharmaceuticals, Inc., 88 Sidney Street, Cambridge, Massachusetts 02139, United States.
  • Medeiros M; Agios Pharmaceuticals, Inc., 88 Sidney Street, Cambridge, Massachusetts 02139, United States.
  • Liu P; Agios Pharmaceuticals, Inc., 88 Sidney Street, Cambridge, Massachusetts 02139, United States.
  • Frank V; Agios Pharmaceuticals, Inc., 88 Sidney Street, Cambridge, Massachusetts 02139, United States.
  • Judd ET; Agios Pharmaceuticals, Inc., 88 Sidney Street, Cambridge, Massachusetts 02139, United States.
  • Biller SA; Agios Pharmaceuticals, Inc., 88 Sidney Street, Cambridge, Massachusetts 02139, United States.
  • Marks KM; Agios Pharmaceuticals, Inc., 88 Sidney Street, Cambridge, Massachusetts 02139, United States.
  • Sui Z; Agios Pharmaceuticals, Inc., 88 Sidney Street, Cambridge, Massachusetts 02139, United States.
  • Reznik SK; Agios Pharmaceuticals, Inc., 88 Sidney Street, Cambridge, Massachusetts 02139, United States.
J Med Chem ; 65(6): 4600-4615, 2022 03 24.
Article en En | MEDLINE | ID: mdl-35293760
Asunto(s)
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Metionina Adenosiltransferasa / Neoplasias Límite: Humans Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Metionina Adenosiltransferasa / Neoplasias Límite: Humans Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos