An Adverse Outcome Pathway for Decreased Lung Function Focusing on Mechanisms of Impaired Mucociliary Clearance Following Inhalation Exposure.

Luettich, Karsta; Sharma, Monita; Yepiskoposyan, Hasmik; Breheny, Damien; Lowe, Frazer J

Luettich, Karsta; Sharma, Monita; Yepiskoposyan, Hasmik; Breheny, Damien; Lowe, Frazer J.

Afiliación

Luettich K; Philip Morris International R&D, Philip Morris Products S.A., Neuchatel, Switzerland.
Sharma M; PETA Science Consortium International e.V., Stuttgart, Germany.
Yepiskoposyan H; Philip Morris International R&D, Philip Morris Products S.A., Neuchatel, Switzerland.
Breheny D; British American Tobacco (Investments) Ltd., Group Research and Development, Southampton, United Kingdom.
Lowe FJ; Broughton Nicotine Services, Earby, Lancashire, United Kingdom.

Front Toxicol ; 3: 750254, 2021.

Article en En | MEDLINE | ID: mdl-35295103

Palabras clave

AOP; NAMs; adverse outcome pathway; ciliary beat frequency; inhalation toxicity; lung function; mucociliary clearance; new approach methodologies

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Prognostic_studies Idioma: En Revista: Front Toxicol Año: 2021 Tipo del documento: Article País de afiliación: Suiza Pais de publicación: Suiza

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