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Efficacy and safety of cotadutide, a dual glucagon-like peptide-1 and glucagon receptor agonist, in a randomized phase 2a study of patients with type 2 diabetes and chronic kidney disease.
Parker, Victoria E R; Hoang, Thuong; Schlichthaar, Heike; Gibb, Fraser W; Wenzel, Barbara; Posch, Maximillian G; Rose, Ludger; Chang, Yi-Ting; Petrone, Marcella; Hansen, Lars; Ambery, Philip; Jermutus, Lutz; Heerspink, Hiddo J L; McCrimmon, Rory J.
Afiliación
  • Parker VER; Research and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK.
  • Hoang T; GW Pharmaceuticals, Cambridge, UK.
  • Schlichthaar H; Study Center, SMO.MD GmbH, Magdeburg, Germany.
  • Gibb FW; Royal Infirmary of Edinburgh, Edinburgh, UK.
  • Wenzel B; APEX GmbH, Munich, Germany.
  • Posch MG; Charite Research Organisation GmbH, Berlin, Germany.
  • Rose L; Zentrum fur Diabetes, Münster, Germany.
  • Chang YT; Early Clinical Development, Research and Early Development, Cardiovascular, Renal and Metabolism (CVRM), BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, MD, USA.
  • Petrone M; Clinical Pharmacology and Safety Sciences, AstraZeneca, Cambridge, UK.
  • Hansen L; Early Clinical Development, Research and Early Development, Cardiovascular, Renal and Metabolism (CVRM), BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, MD, USA.
  • Ambery P; Late Clinical Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
  • Jermutus L; Research and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK.
  • Heerspink HJL; Department of Clinical Pharmacy and Pharmacology, University of Groningen, Groningen, The Netherlands.
  • McCrimmon RJ; School of Medicine, Ninewells Hospital, University of Dundee, Dundee, UK.
Diabetes Obes Metab ; 24(7): 1360-1369, 2022 07.
Article en En | MEDLINE | ID: mdl-35403793
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Diabetes Mellitus Tipo 2 / Insuficiencia Renal Crónica Tipo de estudio: Clinical_trials Límite: Humans Idioma: En Revista: Diabetes Obes Metab Asunto de la revista: ENDOCRINOLOGIA / METABOLISMO Año: 2022 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Diabetes Mellitus Tipo 2 / Insuficiencia Renal Crónica Tipo de estudio: Clinical_trials Límite: Humans Idioma: En Revista: Diabetes Obes Metab Asunto de la revista: ENDOCRINOLOGIA / METABOLISMO Año: 2022 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Reino Unido