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Safety and tolerability of a multilineage-differentiating stress-enduring cell-based product in neonatal hypoxic-ischaemic encephalopathy with therapeutic hypothermia (SHIELD trial): a clinical trial protocol open-label, non-randomised, dose-escalation trial.
Matsuyama, Nao; Shimizu, Shinobu; Ueda, Kazuto; Suzuki, Toshihiko; Suzuki, Sakiko; Miura, Ryosuke; Katayama, Akemi; Ando, Masahiko; Mizuno, Masaaki; Hirakawa, Akihiro; Hayakawa, Masahiro; Sato, Yoshiaki.
Afiliación
  • Matsuyama N; Department of Advanced Medicine, Nagoya University Hospital, Nagoya, Japan.
  • Shimizu S; Department of Advanced Medicine, Nagoya University Hospital, Nagoya, Japan yoshiaki@med.nagoya-u.ac.jp s-shimizu@med.nagoya-u.ac.jp.
  • Ueda K; Division of Neonatology, Center for Maternal-Neonatal Care, Nagoya University Hospital, Nagoya, Japan.
  • Suzuki T; Division of Neonatology, Center for Maternal-Neonatal Care, Nagoya University Hospital, Nagoya, Japan.
  • Suzuki S; Division of Neonatology, Tokyo Women's Medical University Medical Center East, Arakawa-ku, Tokyo, Japan.
  • Miura R; Division of Neonatology, Center for Maternal-Neonatal Care, Nagoya University Hospital, Nagoya, Japan.
  • Katayama A; Division of Neonatology, Center for Maternal-Neonatal Care, Nagoya University Hospital, Nagoya, Japan.
  • Ando M; Department of Advanced Medicine, Nagoya University Hospital, Nagoya, Japan.
  • Mizuno M; Department of Advanced Medicine, Nagoya University Hospital, Nagoya, Japan.
  • Hirakawa A; Department of Advanced Medicine, Nagoya University Hospital, Nagoya, Japan.
  • Hayakawa M; Department of Clinical Biostatistics, Tokyo Medical and Dental University, Bunkyo-ku, Tokyo, Japan.
  • Sato Y; Division of Neonatology, Center for Maternal-Neonatal Care, Nagoya University Hospital, Nagoya, Japan.
BMJ Open ; 12(4): e057073, 2022 04 26.
Article en En | MEDLINE | ID: mdl-35473726
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Hipoxia-Isquemia Encefálica / Hipotermia Inducida Tipo de estudio: Clinical_trials / Guideline Aspecto: Ethics Límite: Humans / Infant / Newborn Idioma: En Revista: BMJ Open Año: 2022 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Hipoxia-Isquemia Encefálica / Hipotermia Inducida Tipo de estudio: Clinical_trials / Guideline Aspecto: Ethics Límite: Humans / Infant / Newborn Idioma: En Revista: BMJ Open Año: 2022 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Reino Unido